There are many reasons one might miss a day taking vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). But what does it mean for us? Here’s what the folks at Chromadex said via email in response to a broad question about missing a day of supplementation or simply taking days off:
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Almost a year ago, airline pilot Dave Crouse shared a life-changing anecdote about welcoming a new baby following seemingly insurmountable fertility challenges. He attributed he and his wife’s success to vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Is Dave correct that NR helped lead to his new baby? Well, last week a new study was published suggesting there might be some validity to Dave’s claim. And in a Facebook comment responding to the new results, Dave explained in further detail how this specific study mirrored his own experience in which he believes NR ultimately helped: “Age-related Oocyte quality was the reason IVF did not work for us”. The following once again is Dave and his wife’s story, “Our Niagen Baby” (Anecdote #11):
A year ago, Nestlé launched a new brand containing Nicotinamide Riboside “NR” (FAQs) (Reviews). We’ve seen their ads in the New York Times — but not much else. Now comes a new video ad wherein Nestlé explains why one should take NR. While NR appears to help consumers in many different ways (see our library of Anecdotes), Nestlé’s positioning is clear:
Dr. Charles Brenner often makes the scientific case for supplementing with Nicotinamide Riboside “NR” (FAQs) (Anecdotes) over NMN (FAQs and Anecdotes). But, he also believes there’s an even simpler reason. In the interview excerpt below, Dr Brenner starts with an explanation of the science and concludes with something many of us can more easily understand:
At the end of June, results from a Phase 3 clinical trial were published showing that a cocktail of metabolic activators including Nicotinamide Riboside “NR” (FAQs) (Reviews) significantly reduced recovery time in mild to moderate COVID-19 patients. Previously, in response to Phase 2 results, Dr. Charles Brenner (who discovered NR as an NAD precursor vitamin) commented on Twitter: “I expect NR was driver of the beneficial effects in ppl“. And now that the full Phase 3 study results have finally been published, Dr Brenner said the following on a mid-July podcast (video embedded below):
Many consumers have reported their skin transformed by vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Some of the most striking examples: Gary’s psoriasis, Anne’s facial spots, and Mike’s younger and smoother skin. (This may explain why there’s a relatively new NR skin care product on the market.) In our latest reader submission, a 44 year-old female whose initials are LP explains in great detail how she believes NR has changed her life (please consider sharing your own NAD+ supplement experience below):
In a recent Nutrition 2021 Conference presentation entitled “Potential Impact of Nicotinamide Riboside (NR) on Maternal Health Outcomes“, UC Davis professor and lactation expert Bruce German PhD explained why vitamin supplement NR (FAQs) (Reviews) might show dramatic effects on human mothers and their offspring in clinical trials he’s currently conducting. The following are key quotes from Dr German:
In a recent conference presentation entitled “Potential Impact of Nicotinamide Riboside (NR) on Maternal Health Outcomes”, Professor and Chemist Bruce German PhD of UC Davis showed the following short but remarkable videos of rodents supplemented with Nicotinamide Riboside “NR” (FAQs) (Reviews):
In response to an audience question regarding the safety of Nicotinamide Riboside “NR” (FAQs) (Reviews), UC Davis professor and chemist Dr. Bruce German who’s testing NR on mothers of preterm infants said the following at the Nutrition 2021 Conference in June:
City of Hope’s Dr. Charles Brenner loves to talk about the science of NAD and Nicotinamide Riboside “NR” (FAQs) (Reviews). And since he discovered NR as an NAD precursor vitamin, he’s well positioned to do so. But many of us non-scientists prefer it when he explains in plain English how NR can potentially improve our lives. Lucky for us, he did so very clearly on a recent podcast (video embedded below):
In response to yesterday’s blog post “Why are Scientists Particularly Focused on Nicotinamide Riboside (NR) and its Impact on Inflammation?“, a Nicotinamide Riboside “NR” (FAQs) (Reviews) consumer shared why he believes scientists might be onto something. His experience is similar to that of Chromadex CEO Rob Fried. The following is David Spaulding’s personal story (please consider sharing your own NAD+ supplement experience below):
Here’s what City of Hope’s Dr. Charles Brenner (discoverer of Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin) said on a recent podcast (video embedded below):
We’ve heard repeatedly that NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) helps people overcome jet lag. What about NAD booster NMN (FAQs and Anecdotes)? Well, on the Joe Rogan podcast earlier this month, Harvard’s David Sinclair said the following:
Here’s what Harvard professor and aging researcher Dr. David Sinclair said about NMN (FAQs and Anecdotes) vs NR (FAQs) (Anecdotes) on a 2020 podcast (video embedded below):
On multiple occasions, we’ve heard that Nicotinamide Riboside “NR” (FAQs) (Reviews) can provide protection for the liver in conditions of metabolic stress. Our latest consumer reviewer clearly agrees. Here’s his story (please consider sharing your own NAD+ supplement experience using the form below):
Last week, Walmart introduced a new 100mg dose of Nicotinamide Riboside “NR” (FAQs) (Reviews) in partnership with Chromadex. While the FDA recommended daily dose of NR is 300mg, we’ve been told that a dose as low as 100mg can also have a therapeutic benefit. It’s reasonable to assume that since NR is expensive, this new cheaper SKU at Walmart is an effort to target a new consumer group. It also might encourage others who could afford the 300mg dose but either balk at the price or are awaiting more clinical data to finally give it a try. Here’s how Chromadex CEO Rob Fried explained the strategy in a recent interview with the TD Ameritrade Network (video embedded below):
It’s widely believed that NAD depletion is a fundamental feature of aging. This is particularly evident in certain diseases that cause accelerated aging. Chromadex CEO Rob Fried discussed this in detail on last week’s Patients Rising Podcast:
In a recent pre-clinical study, scientists at the Ho Lab looked at NAD booster Nicotinamide Riboside “NR” (FAQs) (Reviews) and its impact on cancer growth. One key conclusion: “Collectively, these findings reveal that supplementation with NR alleviates mitochondrial dysfunction and further induces additive anti-tumor immunity in conjunction with ICB (immune checkpoint blockade) treatments”. These findings are somewhat consistent with what Dr. Charles Brenner (NAD expert and discoverer of NR as an NAD precursor vitamin) has said about NR and cancer on various platforms over the last year:
A common complaint from consumers of Nicotinamide Riboside “NR” (FAQs) (Reviews) is cost. Why is it so expensive? Here’s what Chromadex CEO Rob Fried said in response at the recent Benzinga Small-Cap Conference:
While there’s much talk about new Chromadex paid spokesperson and Olympian Ryan Lochte and his claims that Nicotinamide Riboside “NR” (FAQs) (Reviews) helps him with recovery, repair, and energy, we at RaisingNAD are skeptical. We prefer to hear from people like Coach AJ/AJ/Angela J Nealy who receive nothing from stepping forward and sharing their experiences taking NR. And while Coach AJ isn’t an Olympic athlete, she did play in a Professional Women’s Tackle Football League! She’s also a retired Chemistry educator. The following is her story in her own words (please consider sharing your own NAD+ supplement experience using the form below):
Without a Nicotinamide Riboside “NR” (FAQs) (Reviews) product available for pets, some owners are taking matters into their own hands. We’ve heard from a number who’ve chosen to feed NR to their pets hoping to improve their health. Can we expect an NR product for pets? Angela Durazo (actress, former Formula 4 race car driver, former professional triathlete) was hopeful as she reached out to Dr. Charles Brenner on Twitter late last week:
We know that many people are experiencing long haul COVID symptoms. As a result, scientists are looking for possible treatments. One of those scientists is Harvard professor and Alzheimer’s expert Dr. Rudy Tanzi who in partnership with Massachusetts General Hospital recently launched a clinical study looking at Nicotinamide Riboside “NR” (FAQs) (Reviews). Should COVID long haulers be optimistic about Dr Tanzi’s human NR study? Chromadex CEO Rob Fried weighed in on this very issue at the Benzinga Small-Cap Conference yesterday:
A few days ago, Chromadex Chairman Frank Jaksch spoke at the Healthspan Show. In a ~16-minute presentation entitled “Nicotinamide Riboside (NR): The Science of Aging, Cellular Health & NAD+ Precursors”, Jaksch explained NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) in plain English:
Here’s what Chromadex Chairman Frank Jaksch said about NAD boosting supplement NMN (FAQs and Anecdotes) vs Nicotinamide Riboside “NR” (FAQs) (Anecdotes) on yesterday’s earnings call:
Here’s what Chromadex CEO Rob Fried said about vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) and how it impacts his life on yesterday’s earnings call (please consider sharing your own NAD+ supplement experience below):
Over the last year, we’ve heard some incredible stories from readers impacted by taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). While all of these stories are beyond extraordinary (especially Dave & Fertility, Mark & Epilepsy, Gary & Psoriasis), we’re seeing some remarkable consistency. Many people are reporting among other things: faster recovery, better sleep, improved skin, and the return of natural hair color. Today’s submission from Kirk Carter goes a step further (please consider sharing your own NAD+ supplement experience below):
At RaisingNAD, we often highlight Chromadex CEO Rob Fried’s many podcast appearances for a very simple reason. While he never reveals any information that isn’t already publicly available, he does however often explain the merits of supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews) in new, accessible, and more persuasive ways. Last week, he joined the Insider Opportunities podcast to discuss Nicotinamide Riboside (NR):
Last week, we heard from Gary Varvaro who believes Nicotinamide Riboside “NR” (FAQs) (Reviews) helped cure his Psoriasis. Now comes a story from Donna about a friend suffering from Alopecia (see below). These anecdotes appear to add more credibility to the belief that NR can play a role in impacting those suffering from autoimmune diseases (please consider sharing your own NAD+ supplement experience below).
Until now, conventional wisdom has been that your NAD levels start declining in your 20s and plunge between ages 40 and 60. But in the latest episode of Linda Cooper’s “The New 100 Longevity Campaign”, NAD expert Dr. Charles Brenner appears to have evolved his thinking. As a result, we too might have to evolve our own thinking about when to begin supplementing with NAD boosters like Nicotinamide Riboside “NR” (FAQs) (Reviews).
Last year, the NIH launched a pilot study “to test if the dietary supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) can improve immune system function in the blood and skin of people with mild to moderate psoriasis”. According to the study’s principal investigator Dr. Michael Sack, “as the disease (psoriasis) gets more advanced, it can affect the joints, so you can get arthritis. The chronic inflammation can have systemic effects. We’re trying to see in the mild to moderate disease range whether we can prevent (these effects on the entire body)”. The NIH study is expected to be completed on September 30, 2023. In the meantime, we’re fortunate to have the following remarkable submission received yesterday (please consider sharing your own NAD+ supplement experience below):
For most of us, NAD is a foreign concept. But, according to top scientists, it’s critical to human health. Why does NAD remain under the radar? Because it’s not a simple concept. It’s not easily accessible. So, when we at RaisingNAD find an interview or video which explains NAD in plain simple English we jump at the opportunity to share it. The following is an example from last week:
There’s endless discussion online about which NAD boosting vitamin supplement to take — Nicotinamide Riboside “NR” (FAQs) (Anecdotes) or NMN (FAQs and Anecdotes). As a result, potential customers are often left confused without any idea which to choose. The following transcript may provide some clarity.
In numerous recent interviews (Here and Here), top Harvard Alzheimer’s expert Dr Rudy Tanzi discussed plans to initiate 2 human clinical studies using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). In one study, Dr Tanzi will focus on Alzheimer’s patients. And in the other, which was posted on ClinicalTrials.gov earlier this week Dr Tanzi will focus on long-haul COVID patients experiencing persistent cognitive and physical symptoms. You may remember that Dr Tanzi knows a lot about NR through both personal supplementation (“I religiously take Tru Niagen“) AND his association with the NFL’s New England Patriots. As a result, many have been eagerly awaiting these two clinical trials. Here’s more on the COVID trial posted earlier this week:
“As Long As You Have Access To Nicotinamide Riboside (NR), There Is Really No Purpose For Using NMN”
While NAD boosting supplement NMN (FAQs and Anecdotes) remains incredibly popular especially in China, the folks at Chromadex continue to make the case that Nicotinamide Riboside “NR” (FAQs) (Anecdotes) is your better option. Chairman Frank Jaksch made the case in early March. And last week, Dr Andrew Shao weighed in as well in an interview with NUTRA Ingredients Asia. See HERE.
We know that there’s enormous interest in studying Nicotinamide Riboside “NR” (FAQs) (Reviews) in the science community. A quick look at the 50+ ongoing or completed clinical trials says it all. But who are these scientists? Chromadex CEO Rob Fried talked about some of them at the Oppenheimer Health Care Conference yesterday.
What should you expect to feel from supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews)? Do consumers tend to increase their dose over time? Here’s what Chromadex CEO Rob Fried said at the Oppenheimer Health Care Conference yesterday:
A popular YouTube channel called Bestie (3.4m subs) posted a short but substantive video this week with Nicotinamide Riboside “NR” (FAQs) (Reviews) topping a list of “6 Supplements That’ll Help You Build A Better Brain” (Turmeric, Lion’s Mane Mushrooms, Seafood, Vitamin D3). Transcript and video embedded below.
While we’ve heard from many consumers reporting life-changing experiences thanks to supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews), we’re now hearing more and more from pet owners too. This latest story was submitted yesterday (please consider sharing your own NAD+ supplement experience below).
As a public company, Chromadex has few opportunities each year to talk openly with the public about Nicotinamide Riboside “NR” (FAQs) (Reviews). Last evening was one of those times. The following are key quotes from Chromadex CEO Rob Fried and Chairman Frank Jaksch during management’s Q4 2020 earnings call.
In advance of this week’s earnings call, Wall Street analysts at B Riley published a note today on Chromadex and recent developments relating to Nicotinamide Riboside “NR” (FAQs) (Reviews). The following are key excerpts.
We’ve covered this often asked and endlessly debated question repeatedly at RaisingNAD. Scientists say Nicotinamide Riboside (NR) is the better choice — and Nestlé Health Science (a subsidiary of Nestlé), which recently launched a new product with NR as the key ingredient, calls NR: “the most efficient NAD+ precursor“. Yet, NMN (FAQs and Anecdotes) remains incredibly popular. So what should you do? Well, while Chromadex Chairman Frank Jaksch is obviously in the NR camp, he recently made a compelling case in plain English why the choice should be obvious.
Chromadex Chairman: “Mounting Evidence Has Linked Compromised NAD+ Status to the Hallmarks of Aging”
In a rare appearance, Chromadex Founder and current Executive Chairman Frank Jaksch joined the “Cellular Health: The Next Big Market Opportunity“ webcast last week to discuss NAD, Nicotinamide Riboside “NR” (FAQs) (Anecdotes), NMN (FAQs and Anecdotes), aging and more. According to his bio, Jaksch is not your ordinary Executive Chairman. He currently oversees research, strategy, and operations for ChromaDex, with a focus on scientific and novel products for the pharmaceutical and nutraceutical markets. During this webcast, Jaksch had a lot of substantive things to say. As a result, we’re posting a transcript of his entire ~10-minute presentation.
Never before have retail investors been more important to the prospects of small-cap public companies both to drive their businesses and their share prices through the use of social platforms. Let’s leave aside the recent exceptional case of GameStop (GME). But look what retail did to possibly save AMC (ticker: AMC). Incredible. As for small-caps like Chromadex (CDXC) (Nicotinamide Riboside or NR), its management undoubtedly realizes that their vocal community of early adopters (many of whom are also retail shareholders) have played a significant role in driving sales through “Word of Mouth” by sharing their experiences online and encouraging others to give NR a try. Rarely do you see such an active community take daily to Facebook, Reddit, Twitter and even Seeking Alpha (Disclosure) to spread word of the merits of a consumer product. This community represents a remarkable asset. As a result, Chromadex management has agreed to consider community questions for their upcoming March 10th earnings call. While management is obviously limited in what they can say, let’s use this opportunity to tell them what’s on our minds in the comments section below. And, of course, we’ll also enjoy the added benefit of hearing what’s on the minds of other smart investors, scientists, and consumers who are as interested as we are in the future of Nicotinamide Riboside “NR” (FAQs) (Reviews).
Last week, a new Phase 3 human clinical study conducted in Turkey demonstrated that patients with mild-to-moderate COVID-19 who received the standard of care experienced a 3.5 day reduction in recovery time when receiving a nutritional protocol. The nutritional protocol included Nicotinamide Riboside “NR” (FAQs) (Reviews). These Phase 3 results follow Phase 2 data which were published in October 2020. Below are Dr Charles Brenner’s (who discovered NR as an NAD precursor vitamin) evaluation of the two studies and his opinion on the role of NR.
During a webcast yesterday titled “Cellular Health: The Next Big Market Opportunity“, Nestlé Health Science’s Joelle Legree spoke at great length explaining the strategy behind the recent launch of Celltrient. Of course, Celltrient is Nestlé Health’s (a Nestlé subsidiary) new brand focused on cellular health. And, for those interested in raising NAD levels, one of Celltrient’s three new products “Celltrient Energy” contains Nicotinamide Riboside “NR” (FAQs) (Reviews). How does Nestlé Health and its team of scientists feel about the NR vs NMN debate? Key quotes: