Raising NAD+ (with B3 Vitamins)

Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Why Consider a Niagen+ IV (NR IV) Versus Simply Taking Oral Supplement Niagen (NR)?

During last week’s Q3 earnings call, a Wall Street analyst asked Chromadex CEO Rob Fried to compare the bodily impact of the new Niagen+ IV to NAD+ boosting supplement Niagen (Nicotinamide Riboside “NR” (FAQs) (Anecdotes)). Here’s the question followed by CEO Fried’s response:

Why Does Fertility Expert Dr. Aimee (“The Egg Whisperer”) Recommend NR to All of Her Patients Looking to Improve Egg Quality?

As we know, Harvard-trained fertility expert Dr. Aimee (“the egg whisperer”) is a big believer in taking a variety of health supplements to improve egg quality. One of those supplements is NAD+ booster Nicotinamide Riboside “NR” (FAQs)  (Anecdotes). Dr. Aimee made the case for NR on a recent episode of the Pregnantish podcast

Nicotinamide Riboside (NR) IV Anecdote #1: “Honestly I Feel Really Great Today”

Over the last couple of years, we’ve heard a slew of anecdotal reports claiming NAD+ IVs provide a variety of significant benefits (Link). What about consumer experiences with the new Nicotinamide Riboside “NR” (FAQs) (Reviews) IV? Here’s a frank, first person account from Bill Walker (also an oral NR consumer):

What’s the Case for Niagen+ IVs (NR IVs) Over NAD+ IVs?

While we mostly focus here on oral vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), there’s growing demand for raising NAD levels through NAD+ IVs. And, if you happen to be one of those who enjoy NAD+ IVs, you now have what might be a better alternative: Niagen+ (NR) IVs, which deliver NAD+ booster Nicotinamide Riboside “NR”. Whats the case for Niagen+ (NR) IVs over NAD+ IVs? Below are results of a clinical study comparing Niagen+ (NR) IVs and NAD+ IVs followed by related comments from Chromadex CEO Rob Fried (seller of Niagen+ (NR) IVs) at an August investor conference:

Anecdote #37: “This (NR) has definitely made a difference in my energy levels”

As we await clinical trial results to confirm individual claims about NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), we’re always interested to see if there are any consistencies in consumer anecdotal reports. Today, we hear from Coach Beede who posted the following earlier today (reposted here with permission):

Anecdote #36: Nicotinamide Riboside (NR) Cleared Mild Psoriasis

In response to yesterday’s Anecdote #35: “I’ve noticed…a dramatic reduction in my psoriasis” (Link), my friend Jeff Gilligan commented that he too enjoyed a similar experience after taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Here’s what he said:

Anecdote #35: “I’ve Noticed…a Dramatic Reduction in My Psoriasis”

This is not the first time we’ve heard from someone claiming that vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) helped treat psoriasis. Gary Varvaro told us the same (Link). Some might find these claims plausible considering we’ve also heard from many others reporting remarkable skin benefits after taking NR  (Link). Of course, until we have positive results from human clinical trials, we won’t know whether these claims have any credibility. That said, here is yet another powerful personal experience submitted to us by NR consumer Lawrence Lane:

What Explains the Delay in Releasing Results of the NR / Long COVID Clinical Study?

We all know someone suffering from Long COVID. And, if you’re like me, you’ve been waiting patiently for results of the Harvard/MGH Long COVID clinical study (Details) evaluating NAD+ boosting supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) as a possible treatment. So, what’s the status of the study? Chromadex CEO Rob Fried explained during an investor presentation at the end of August:

Dr. Oz Takes Nicotiname Riboside “NR”; Asks Wellness Doctor Which Patients Benefits the Most

A few years ago, Dr. Oz shared that his mother was suffering from Alzheimer’s disease. And, at the suggestion of Alzheimer’s expert Dr. Rudy Tanzi, Dr. Oz had his mom taking a variety of vitamins including NAD+ boosting supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). In late July, Dr. Oz interviewed health and wellness expert Dr. Darshan Shah, asked which patients he prescribes NR to, and who benefits the most. Here’s what he said:

Growing Scientific Evidence Suggesting NR May Help Alzheimer’s Patients

In early August, an article at the Brighter Side discussed a 2022 study suggesting that NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) may impact metabolic pathways involved in neurodegenerative diseases like Alzheimer’s. We covered the principal investigator on this study, Dr. Martens, and the results of his study here. So, what studies do we now have demonstrating NR might be helpful for Alzheimer’s patients?

During the Belichick Era, New England Patriots were Taking Nicotinamide Riboside “NR”

During an appearance on the “The Optispan Podcast with Matt Kaeberlein”, NAD+ expert Dr. Charles Brenner (FAQs) said the following about the NFL’s New England Patriots taking vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews):

Dr. Andrew Huberman’s Latest Update on Taking NMN & NR. What Impact Do They Have?

During last week’s Huberman Lab podcast with Dr. Peter Attia, Dr. Andrew Huberman (FAQs) shared his current regimen of NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs)  (Anecdotes) and NMN (FAQs and Anecdotes). Here’s what he said:

Where Does Dr. Peter Attia See a Possible Signal in Support of NR & NMN Supplementation?

For as long as I can remember, Dr. Peter Attia has been a vocal critic of NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs)  (Anecdotes) and NMN (FAQs and Anecdotes). But what would change his mind? Here’s what he said on the Huberman Lab podcast last week:

How Do You Decide Which NAD+ Booster Brand to Purchase?

I started writing this site long ago because the world of NAD+ boosters was so confusing. I was sold on the need to take an NAD+ booster, but struggled to decide which one. During a recent Whitney Cummings podcast, the host and her guest (Fertility expert Dr. Aimee “The Egg Whisperer”) explained how they each individually arrived at a decision:

Anecdote #34: Dr. Aimee (“The Egg Whisperer”) Claims NR Helps Her Concentration, Memory, Sleep…

For those interested in improving egg quality and fertility chances, you’ve probably heard Harvard-trained fertility specialist Dr. Aimee’s (“The Egg Whisperer”) enthusiasm for NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (Reviews). And, while Dr. Aimee is no longer trying to get pregnant herself, she takes NR nonetheless. Below she explains why on the Whitney Cummings podcast:

Anecdote #33: “I Fully Credit Becoming Pregnant Naturally at 40 with Taking this Product (NR)

A few weeks ago, prominent podcaster Whitney Cummings (441k subscribers) hosted fertility expert Dr. Aimee (“The Egg Whisperer”) in a segment entitled “How to Get Pregnant”. Here’s what Whitney said about vitamin supplement Nicotinamide Riboside “NR” (Reviews):

If You’re Taking Nicotinamide Riboside “NR”, Should You Worry about Methylation?

As with many things NAD+ related, there’s confusion among consumers as to whether taking oral supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) might cause methyl depletion. Not according to the following:

How Much NMN is in Your Bottle?

A few years ago, a surprising study showed that a large majority of the top 22 NMN brands sold on Amazon contained much less NMN than advertised (Link). Fast forward to mid-2024, a new study has found similar results (and only one NMN brand from the two studies overlapped). Here’s more from the 2024 NMN study:

NAD+ Injection Anecdote #1: “More Energy, Less Brain Fog” (MCAS)

As you know, there are a number of ways to raise your NAD+ levels. Most consumers choose oral supplements Nicotinamide Mononucleotide “NMN” (FAQs) and/or Nicotinamide Riboside “NR” (FAQs) (Reviews). Some choose an NAD+ IV (FAQs). And then there are others who choose an NAD+ injection. Here’s a submission from Joan Vignocchi that will hopefully benefit others:

Fertility Expert Dr. Aimee (“The Egg Whisperer”): Here’s Why Maintaining NAD+ Levels is Critical

During a recent episode of the Tara Lipinski podcast, fertility expert Dr. Aimee (aka “The Egg Whisperer”) was asked to explain NAD+, and why it’s important for everyone. Here’s what she said (transcript and video below):

Does Dr. Aimee (The Egg Whisperer) Recommend Nicotinamide Riboside “NR” for Patients Breastfeeding?

During last week’s episode of “Ask Dr. Drew”, fertility expert Dr. Aimee (aka “The Egg Whisperer”) was asked whether she recommends that patients who are breastfeeding supplement with Nicotinamide Riboside “NR” (Reviews). Here’s what she said (transcript and video below):

Should You Take Nicotinamide Riboside “NR” Once Pregnant? Here’s What Dr. Aimee (“The Egg Whisperer”) Recommends

During a recent episode of the Tara Lipinski podcast, fertility expert Dr. Aimee (aka “The Egg Whisperer”) was asked whether you should continue taking NAD+ booster Nicotinamide Riboside “NR” (Reviews) after successfully getting pregnant. Here’s what she said (transcript and video below):

What Dose of Nicotinamide Riboside Does Dr. Aimee (The Egg Whisperer) Recommend to Fertility Patients?

During last week’s episode of “Ask Dr. Drew”, fertility expert Dr. Aimee (aka “The Egg Whisperer”) was asked how much Nicotinamide Riboside “NR” (Reviews) she recommends her patients take daily. Here’s what she said (transcript and video below):

Does Dr. Aimee (The Egg Whisperer) Recommend Nicotinamide Riboside “NR” for Egg Freezers?

During an episode of “Ask Dr. Drew” this past week, fertility expert Dr. Aimee (aka “The Egg Whisperer”) was asked about Nicotinamide Riboside “NR” (Reviews) for those wanting to freeze their eggs. Here’s what she said (transcript and video below):

Does Dr. Aimee (The Egg Whisperer) Recommend Nicotinamide Riboside “NR” for Sperm Health?

During this week’s Tara Lipinski podcast, fertility expert Dr. Aimee (aka “The Egg Whisperer”) was asked about Nicotinamide Riboside “NR” (Reviews) for sperm health. Here’s what she said (transcript and video below):

Anecdote #32: Goodbye Oily Skin

The number of consumers claiming extraordinary skin improvements from vitamin supplement Nicotinamide Riboside “NR” (Reviews) continues to grow. The latest comes from Ryan Schroder (a PhD in Biochemistry):

“My Daily Workouts are Literally Exactly the Same as My Workouts Were 30 years Ago” (Nicotinamide Riboside)

During a podcast appearance last week, Chromadex CEO Rob Fried shared his own experience taking NAD+ boosting supplement Nicotinamide Riboside “NR” (Anecdotes). Here’s what he said (audio below):

“Kesha” the Cat’s Health Improved After Taking NMN

We’ve heard from many consumers claiming all sorts of benefits after taking NAD+ boosting supplements Nicotinamide Riboside “NR” (Anecdotes) and Nicotinamide Mononucleotide “NMN” (Anecdotes). More and more, we’re hearing from pet owners sharing their NMN pet anecdotes. Here’s the latest from a cat owner:

Could a Nicotinamide Riboside (NR) Skin Cream Be More Effective than a Nicotinamide/Niacinamide Skin Cream?

We’ve recently heard many consumer anecdotes claiming extraordinary skin improvements after supplementing with oral vitamin Nicotinamide Riboside “NR” (FAQs) (Reviews). And, since fellow B3 vitamin Niacinamide/Nicotinamide has long been a staple of prominent skin creams, our remarkable Nicotinamide Riboside “NR” consumer anecdotes might not be terribly surprising. We’ll, of course, have to wait for the results of human trials for an answer. In the meantime, a new NR skin cream was recently introduced by a South Korean company. How does that NR skin cream compare to Niacinamide/Nicotinamide creams?

3 Consumers Explain How Nicotinamide Riboside “NR” Brought Relief from RLS

We’ve heard from many consumers telling us remarkable stories of their experiences taking B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Some claim NR brought relief from struggles with Restless Legs Syndrome “RLS”. See below:

7 Consumers Explain How Nicotinamide Riboside “NR” Improved their Energy Levels

We’ve heard from many consumers telling us remarkable stories of their experiences taking B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). One of the most common claims people make is of increased, and sustained energy. See below:

Recently Completed Pre-Clinical Trials Studying Nicotinamide Riboside

From yesterday’s Chromadex (sellers of Nicotinamide Riboside “NR” (FAQs) (Reviews)) earnings call:

What Clinical Studies on Nicotinamide Riboside is Chromadex Most Excited About?

From yesterday’s Chromadex (sellers of Nicotinamide Riboside “NR” (FAQs) (Reviews)) earnings call:

Is Nicotinamide Riboside the Same as Niacin?

Niacin and Nicotinamide Riboside “NR” (FAQs) (Anecdotes) are both forms of Vitamin B3. How are they different?

Should You Take Breaks from B3 Vitamin Nicotinamide Riboside NR?

Consumers often wonder whether it’s important to take breaks from supplements like Nicotinamide Riboside “NR” (FAQs) (Reviews). Years ago, someone asked NAD+ expert Dr. Charles Brenner (FAQs) about this very issue. And this weekend he gave a little more clarity:

B3 Vitamin Nicotinamide Riboside (NR) Likely Won’t Extend Lifespan, But Can Potentially Help You “Age Better”

While some position NAD+ boosters Nicotinamide Riboside “NR” (FAQs) (Reviews) and NMN (FAQs) as anti-aging supplements, NAD+ expert and NR consumer Dr. Charles Brenner (FAQs) goes to great lengths to focus on more realistic expectations. Here’s what he said on the Genius Life Podcast earlier this week:

Explaining NAD to a Non-Scientist

You’ve likely heard the acronym, N. A. D., but you don’t really know what it means. Well, you’re not alone. Nicotinamide Adenine Dinucleotide, what? To add to our challenge, NAD scientists often struggle to explain it themselves. But, this week, on the Genius Life podcast, NAD+ scientist Dr. Charles Brenner (FAQs) made it a little more accessible:

Can Nicotinamide Riboside Help Expedite Injury and Workout Recovery?

Back in 2020, Dr. Charles Brenner (FAQs) joined The Genius Life podcast to discuss NAD+, and vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). At the time, Brenner addressed specific safety concerns. This week, during a return visit, Brenner offered new comments on a clinical trial he’s particularly interested in:

What Are Natural Sources of Nicotinamide Riboside?

Consumers often wonder whether they can raise their NAD+ levels by simply eating certain foods rich in NAD+ precursors. Unfortunately, NAD+ precursors like Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and Nicotinamide Mononucleotide “NMN” (FAQs and Anecdotes) are only found in trace amounts in food:

FAQs on NAD+ Supplement Nicotinamide Riboside (NR) and Sleep Benefits

We know that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) improves sleep in mice. But what about humans? The following are a number of anecdotes from consumers claiming to have experienced sleep benefits from NR supplementation:

What’s the Most Underrated Benefit of NAD+? “Skin”

Over the years, we’ve heard some remarkable anecdotes from consumers claiming skin benefits from taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Could there be some basis for these claims? NAD+ expert Dr. Charles Brenner (FAQs) shared some news on this very topic during an appearance on the Darin Olien podcast this week:

Should I Take Nicotinamide Riboside with Food?

One of the most common questions consumers have about NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) is whether to take it with or without food. Here’s what NAD+ expert Dr. Charles Brenner (FAQs) has said:

What Can You Expect from Taking Nicotinamide Riboside “NR”?

You might have read the many life changing anecdotes we have from consumers taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). But how do NAD+ scientists describe their own NR experiences? Here’s what Dr. Charles Brenner (FAQs) said on a podcast last month:

Instead of an NAD+ IV, How About a Nicotinamide Riboside “NR” IV?

You’ve likely heard of NAD+ IVs. What about NR IVs? During an episode of the “Forever Young” podcast last month, Chromadex CEO Rob Fried was asked about future opportunities beyond oral supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Here’s what he said:

An Update on Recent Clinical Trials Using Nicotinamide Riboside “NR”

During last night’s earnings call, Chromadex CEO Rob Fried discussed the results of recent clinical trials using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR”  (FAQs) (Anecdotes). Here’s what he said:

Should the New Niacin Study Concern Consumers of NAD+ Booster Nicotinamide Riboside (NR)?

As you probably know, there’s a lot of Niacin in Western diets. So, when a new, potentially concerning Niacin study was published last week, the media sounded the alarm, and word spread quickly. Furthermore, those taking NAD+ boosters Nicotinamide Riboside “NR”  (FAQs) (Anecdotes) and/or Nicotinamide Mononucleotide “NMN” (FAQs and Anecdotes) began to wonder whether they, too, were at risk. But, as it turns out, there are some serious flaws in this whole narrative.

Dr. Drew: “If I Had Access to Only One Supplement, NR Would Be That Supplement”

Earlier this week, Dr. Drew interviewed NAD+ expert Dr. Charles Brenner (FAQs) to discuss NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Here are some highlights on the importance of NAD+, NR vs NMN, NR dosage, and more (full video interview embedded below):

An Update on Parkinson’s Studies Using Nicotinamide Riboside

We’ve written a lot about ongoing clinical trials testing NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) for Parkinson’s patients. Fortunately, Chromadex (NR sellers) CEO Rob Fried gave the following update on those trials at an investor conference earlier this week:

How Much Nicotinamide Riboside “NR” Should You Take?

A common question consumers have is how much Nicotinamide Riboside “NR” (FAQs) (Anecdotes) to take daily. During an appearance on “The Story of a Brand” podcast, Chromadex (sellers of NR) CEO Rob Fried offered the following:

How Can You Tell if Supplementing with Nicotinamide Riboside (NR) is Helping You?

While obvious to some, many consumers often wonder whether the supplement they’re taking is positively impacting them. If the latter is you, you might find the following useful. During an appearance on “The Story of a Brand” podcast, Chromadex (sellers of NR) CEO Rob Fried had some advice for those taking vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and wondering if it’s working:

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