Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Frequently Asked Questions (FAQs) on NAD Boosting Vitamin B3 Supplement Nicotinamide Riboside (NR)

If you’re considering taking B3 vitamin Nicotinamide Riboside “NR” (FAQs) (Reviews) over NMN (FAQs) by supplementing with brands such as Celltrient Energy, Roman Life, Niagen etc, you’ve come to the right place. We have answers to many of your pressing questions:

Questions (More Detailed Answers Below):

  • What’s NAD+ (N.A.D.)? (Link)
  • What is NAD+ boosting B3 vitamin Nicotinamide Riboside NR? (Link)
  • Is NR safe? (Link)
  • Any side effects from taking it? (Link)
  • Why does NAD+ expert Dr. Charles Brenner take NR? (Link)
  • What does Dr. Charles Brenner feel from taking NR? (Link)
  • What’s the #1 consumer reported benefit from taking it? (Link)
  • Want to hear some life-changing consumer testimonials? (Link)
  • What age should I consider taking it? (Link)
  • What dose should I take? (Link)
  • What dose does the Niagen (NR brand) team take? (Link)
  • What time of day should I take it? (Link)
  • Do I take it with or without food? (Link)
  • Is there added benefit to taking it sublingually? (Link)
  • If I can’t swallow, can I dissolve it in water? (Link)
  • Does a higher dose lead to a greater increase in NAD+ levels? (Link)
  • Should I take 2 capsules at once OR space them out? (Link)
  • How long does it take to impact me? (Link)
  • What if I take it but feel nothing? (Link)
  • What if I miss a day? (Link)
  • Do I benefit from taking breaks from it? (Link)
  • Does it promote cancer tumor growth? (Link)
  • Do athletes take it? New England Patriots! (Link)
  • Does it impair workout muscle performance? (Link)
  • Why would a healthy 20-year old take it? (Link)
  • Does it help avoid or lessen hangovers? (Link)
  • Does it help fight “jet lag”? (Link)
  • Does it improve egg quality, fertility chances? (Link)
  • Can it help mothers with lactation? (Link)
  • Can it improve skin? (Link)
  • Can it help restore natural hair color? (Link)
  • Can I feed it to my pets? (Link)
  • Can it help those suffering from ALS? (Link)
  • Can it help those suffering from Alzheimer’s? (Link)
  • Can it help those suffering from neuropathy? (Link)
  • Can it help those suffering from Long COVID? (Link)
  • Can it help increase testosterone levels? (Link)
  • Can it help reduce Triglycerides? (Link)
  • Do I need to refrigerate it? (Link)
  • Is it safe to consume an expired bottle? (Link)
  • Why is it so expensive? (Link)
  • If Niacin boosts NAD, why pay up for NR? (Link)
  • What about NR vs NMN? (Link)
  • Is there a lab test to measure NR’s impact? (Link)
  • Does taking NR interfere with the natural production of NAD+? (Link)
  • How can you measure your NAD+ levels? (Link)
  • Do I benefit from taking Resveratrol with NR? (Link)
  • Do I benefit from taking Pterostilbene with NR? (Link)
  • Should I consider an NAD+ IV drip? (Link)
  • Does fasting increase NAD+ levels? (Link)

What’s NAD and why does it matter for your health?

  • This video from Nestlé explains it well (Link)
  • So does this one from Thorne (Link)
  • NAD explained in 5 Tweets (Link)
  • Mount Sinai medical doctor explains NAD (Link)

At what age should you start worrying about NAD decline?

  • Here’s the latest thinking (Link)

What is NAD boosting vitamin supplement Nicotinamide Riboside (NR)?

  • It’s a form of vitamin B3 that’s been proven to raise your NAD levels.
  • Scientists believe that as you age your NAD levels decline leaving you more vulnerable to disease.
  • There are now hundreds of peer reviewed published scientific studies showing that NAD levels are dysregulated in many diseases or conditions (Link)
  • But by taking NAD boosters like vitamin supplement Nicotinamide Riboside (NR) you improve your chances of living a healthier life.
  • NAD is naturally occurring in milk and in certain foods — but only in small, trace amounts (Link)
  • So, diet alone doesn’t provide enough NAD to meaningfully restore disrupted NAD production.
  • That’s why many consumers take NAD boosting vitamin supplements such as Celltrient Energy, Roman Life, Niagen etc where the key ingredient is high concentrations of NR which later converts to NAD in your body.
  • Here’s a short video showing a mouse on NR crushing a placebo mouse (Link)

Is the NR in brands like Celltrient, Roman Life, Niagen safe?

  • Scientists say it is (Link).
  • It’s also been deemed safe by many regulatory bodies (Link).
  • This is not the case for NAD booster NMN (Link)

Any known side effects from taking NR?

  • There’ve been no reports of consumers experiencing serious adverse effects from taking NR (Link)
  • There’s no evidence NR promotes cancer tumor growth (Link)

Why do consumers take NR?

  • The #1 consumer response is feeling more sustained energy (Link)
  • It’s not a short term fix like coffee (Link)
  • The NFL’s New England Patriots take it for energy, recovery, and focus (Link)
  • Consumer submitted reviews #1 – #25 (Link)
  • Here’s why I take it (Link)

How much NR should I take?

  • The FDA recommended daily dose is 300 mg — but many admit to taking far more (Link)
  • Dr. Charles Brenner (who discovered NR as an NAD precursor vitamin) has indicated that doses used in therapeutic trials are generally 1-2 grams per day and that people taking more than 500 mg per day often split their daily dose into a morning and evening dose (Link)

What’s the best time of day to take NR?

  • Dr. Brenner has indicated that people generally take NR in the morning (Link)

Should I take NR with or without food?

  • Dr Brenner says you can take it with OR without food (Link)

Is there added benefit to taking NR sublingually?

  • It’s conceivable — but there’s no good data (Link)

How long until NR impacts me?

  • It varies by individual — but typically anywhere from a few weeks to a couple of months (Link)

What if I take NR but feel no impact?

  • Here’s one MD’s explanation why he takes NR despite feeling nothing (Link)

What if I miss a day of NR?

  • NAD+ levels only begin to decline after several days off (Link)

Do I benefit from taking breaks from NR?

  • Dr. Brenner says “no” (Link)

Do athletes take NR?

  • Yes (Link)
  • Professionals and non-professionals do (Link) including the NFL’s New England Patriots (Link)

Why would a healthy 20-year old take NR?

  • For various reasons (Link)

Does NR help avoid or lessen hangovers?

  • Dr Brenner increases his dose prior to Passover Seders where he knows he’ll be consuming unusual amounts of alcohol (Link)

Does NR help overcome “Jet Lag”?

  • This is one of the few things NAD experts Dr. David Sinclair and Dr. Charles Brenner agree on (Link)

Does NR improve egg quality?

  • This Harvard trained fertility expert believes so (Link)

Can NR help mothers with lactation?

  • This lactation expert says growing evidence suggests the answer is “yes” (Link)

Can NR help improve skin?

  • 8 remarkable consumer anecdotes (Link)

Can NR help restore natural hair color?

  • Lots of anecdotal evidence suggests it can (Link)

Can I give NR to my PETS?

  • Everything you need to know (Link)

Do I need to refrigerate NR?

Why is NR so expensive?

  • Because the NR manufacturing process is expensive (Link)

If Niacin boosts NAD levels, why pay up for NR?

  • There’s good reason (Link)

What about NR vs NMN?

  • If you’re concerned about safety, NR appears the better choice (Link)

Is there a lab test to measure the impact of taking NR?

  • An expert weighs in (Link)

Do I benefit from taking Resveratrol with NR?

  • Dr. Sinclair’s former MIT colleague weighs in (Link)

Do I benefit from taking Pterostilbene with NR?

  • Unfortunately, it’s not a good combination (Link)

Should I consider an NAD IV drip?

  • There’s no reason to IV when a comfortable alternative already exists (Link)
  • Joe Rogan disagrees (Link)

Related:

  • Nicotinamide Riboside “NR” (FAQs) (Consumer Reviews)
  • Nicotinamide Riboside “NR” and Alzheimer’s (FAQs)
  • Nicotinamide Riboside “NR” and Fertility (FAQs)
  • Nicotinamide Riboside “NR” and Pets (FAQs)
  • Nicotinamide Mononucleotide “NMN” (FAQs)
  • NAD+ IV Drip Therapy (FAQs)

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2 Comments

  1. Don R Hansen

    Will NR reduce the effectiveness of Metformin? (Niacin supposedly does)

  2. Robert

    WOW – Fantastic site, (thank you!). I’ve had 4 IV drips of NAD+ with *very* clear gains in cognition, energy, drive + sense of wellbeing – basically my brain felt 20-30 years younger. But as a “returning” student on a budget, I want/need to economize. Q1: Presuming my NAD levels are a mid-50 male’s levels, will taking IV drips “level off” in effectiveness after an initial build up? Q2: If I do IV drips 2 x month, along with daily oral intake of NAD, would that be a good way to (re-) optimize NAD levels, or should I “boost” with NAD+ IV’s more frequently for an initial period? Q3: I’m considering going to Mexico for a 5-day “series” of larger dose NAD+ drips, does this “move the ‘needle'” for folks with cognitive issues (TBI, brain fog, etc) ? Q4: I’m looking for a way to make IV financially sustainable. At my drip clinic, one nurse mentioned her lawyer client (who’s in almost daily) is so blown away by NAD+ drips, he’s now studying to be a nurse so he can get legal clearance to self-administer and save $. Grateful for any thoughts on making IV drips more feasible (like a “drip collective”?). (Now, if only I can convince my 92 y.o. mom to try it). I live in the SF Bay Area of CA. Grateful for your obvious dedication and hard work — may it come back to you!

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