Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

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The world of NAD+ supplements is confusing. This site is an effort to make sense of it. Please consider sharing it with others. If you have questions or comments, please email me. I respond promptly. Thank you for visiting.

Dr. Huberman Explains the FDA’s NMN Ban

Last week, Stanford neuroscientist Dr. Andrew Huberman (FAQs) spent much of his appearance on the Joe Rogan podcast explaining the FDA’s recent ban of NAD+ boosting supplement NMN (FAQs, Anecdotes). Dr. David Sinclair recently tweeted about the ban HERE. And, here’s Dr. Huberman explaining the situation to Joe Rogan:

FAQs on Dr. Andrew Huberman — His Thoughts on NMN and NR

While admittedly not an NAD+ expert, Stanford neuroscientist Dr. Andrew Huberman is very interested in the NAD+ space. He currently takes NMN (FAQs and Anecdotes). And since he has a wealth of knowledge, access to NAD experts, and a huge platform, we’re keeping track of his latest comments. Here’s what he’s recently said:

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What Does Dr. Huberman Feel After Taking NMN?

On two occasions we’re aware of, Stanford neuroscientist Dr. Andrew Huberman (FAQs) has discussed his experience taking NAD+ boosting supplement NMN (FAQs and Anecdotes). The first time was on Twitter. The second time was on the Joe Rogan podcast. You can see both below:

Dr. Huberman Believes in NAD+ Boosters NR and NMN

Here’s what Stanford neuroscientist Dr. Andrew Huberman (FAQs) told podcaster Joe Rogan last week in explaining why he takes NAD+ boosting supplement NMN (FAQs and Anecdotes), and also believes in fellow NAD+ booster NR (FAQs) (Anecdotes):

Is There Definitive Proof NMN Doesn’t Enter Cells?

NAD+ expert Dr. Charles Brenner (FAQs) often says that NAD+ boosting supplement NMN (FAQs and Anecdotes) doesn’t enter cells. What’s his proof? Take a look:

Dr. Andrew Huberman to Joe Rogan: “I Think That Keeping NMN on the Market as a Supplement Would Be Wonderful”

Stanford neuroscientist, Dr. Andrew Huberman (FAQs) was a guest on the Joe Rogan podcast yesterday. Here’s what he said about NAD+ boosting supplement NMN (FAQs, Anecdotes):

Gwyneth Paltrow Joins the Hollywood Craze for NAD+ IVs. But Does She Sound Credible?

Much to the continued surprise of NAD+ experts, NAD+ IVs (FAQs and Anecdotes) are increasingly popular in the Hollywood community. We know about Kendall Jenner, and Justin and Hailey Bieber (see video below). The latest example? Gwyneth Paltrow. But are her recent explanations for periodic NAD+ IVs credible? Science-based? We’ll leave that for you to decide:

Frequently Asked Questions (FAQs) and Anecdotes on Nicotinamide Mononucleotide “NMN”

Though it’s increasingly difficult to purchase NAD+ boosting supplement Nicotinamide Mononucleotide “NMN” (versus other NAD+ precursors like Nicotinamide Riboside “NR” (FAQs) (Anecdotes)), you might find the following useful:

Here’s the Missing Clip on Supplements from Alzheimer’s Expert Dr. Rudy Tanzi’s Recent Appearance on the “In The Bubble” Podcast

If you listened to former White House advisor Andy Slavitt’s recent podcast “Are We on the Verge of Curing Alzheimer’s?“, you learned a lot. But you were also surprised by the way it ended. Slavitt was joined by world renowned Alzheimer’s experts, Dr. Paul Aisen and Dr. Rudy Tanzi. Toward the end of the podcast, Dr. Aisen advised those interested in taking measures to prevent Alzheimer’s that taking supplements made no sense. You’d have expected a response from Dr. Tanzi, since we know he disagrees. But none came. So, we, at RaisingNAD reached out to Dr. Tanzi, and learned that his response to Dr. Aisen was edited out. Fortunately, the folks at Lemonada were kind enough to share Tanzi’s comments with us, which we’ve embedded and transcribed below:

Should Consumers Start Taking NR, Especially if They Have Risk Factors for Alzheimer’s? A Scientist Weighs In

You’re likely aware of the recently published and very encouraging clinical results using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) in a study relating to Alzheimer’s. If you missed it, you can catch up here and here. Late last week, the lead investigator, Dr. Christopher R. Martens gave a podcast interview to discuss results of his study. Here’s a key excerpt (podcast embedded below):

You Might Be Surprised to Hear How NR Seller Chromadex Described Competitor NMN During Last Night’s Earnings Call

During last night’s quarterly earnings call, a fund manager asked Chromadex CEO Rob Fried about the efficacy of NMN (FAQs, Anecdotes). NMN is, of course, an NAD+ boosting supplement that competes with Chromadex’s NAD+ booster Nicotinamide Riboside (FAQs + Dosage) (Life-Changing Anecdotes). Here’s what CEO Fried said in response:

Most Popular at RaisingNAD

At RaisingNAD, we have limited science background. So, this site is devoted to helping other non-scientists quickly understand the complex and confusing world of NAD+ health supplements like NMN and NR. Please consider sharing this site with anyone you think might find it useful. And, if this site helps you, and you’d like to support our efforts, please contact us. We’d be grateful. The following are our most popular blog posts:

In an Interview, Scientist Discusses Key Findings from His Alzheimer’s Related Study Using NR

In late December, Dr. Christopher R. Martens and his team at the University of Delaware published results of a study using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). The title of their paper is “Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin“. You can read it HERE. Earlier this week, Dr. Martens was interviewed by MedicalResearch.com wherein he discussed his findings. Here are some excerpts:

Video: First Human Trial Shows NR Can Enter The Brain And Reduces Biomarker For Alzheimer’s

Late last year, results of a human clinical study were published supporting the idea that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes), upon reaching the brain, can alter the metabolism of certain biological pathways involved in neurodegenerative diseases like Alzheimer’s. For the non-scientist, the following articles (one and two) explain the findings in plain English. For those interested in the science, see the following short video (6 minutes):

Expert: “We Think that Higher NAD Status is Really Important for Prevention of Cancer”

During an interview earlier this week, NAD+ expert, Dr. Charles Brenner (FAQs) was asked whether daily consumption of vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) brought cancer risk. Here’s what he said:

What Does NAD+ Expert Dr. Charles Brenner Eat for Breakfast along with his Nicotinamide Riboside (NR)?

If you watch interviews with NMN expert Dr. David Sinclair, you’ll find he often discusses his breakfast routine (see below). What about NR expert Dr. Charles Brenner (FAQs)? Well, typically, his mantra on breakfast is “you do you”. But, earlier this week, we finally got more details.

Expert: NAD+ IVs Are Just Mega Dosing Nicotinamide Riboside (NR). They Can Do That Orally

During a podcast interview earlier this week, Dr. Charles Brenner (FAQs) was asked about NAD+ IVs (FAQs and Anecdotes). As both an NAD+ expert, and the discoverer of Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) as an NAD+ boosting vitamin, Dr. Brenner is often asked about this increasingly popular treatment. Here’s Dr. Brenner’s most recent take:

FAQs on the Potential for Nicotinamide Riboside (NR) in Parkinson’s Patients

Parkinson’s expert Dr. Charalampos (Haris) Tzoulis is actively running clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a possible treatment option for Parkinson’s patients. He’s clearly optimistic. And, as you’ll see below, this is consistent with what we’ve heard from NAD+ experts Dr. Charles Brenner (FAQs) and Dr. David Sinclair in regards to their preferred NAD+ precursors, NR and NMN, respectively:

Parkinson’s Expert: Here’s My Advice for Consumers Looking to Prevent Neurological Disorders Such as Parkinson’s

During the Q&A portion of last week’s presentation, Parkinson’s expert Dr. Charalampos (Haris) Tzoulis was asked if, based on his ongoing clinical trials studying vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes), he had any advice for consumers looking to prevent neurological disorders such as Parkinson’s. Here’s what he said:

Parkinson’s Expert: Why Did We Use Nicotinamide Riboside (NR) in Our Parkinson’s Human Clinical Study?

Dr. Charalampos (Haris) Tzoulis, a Parkinson’s expert, and Professor of Neurology and Neurodegeneration at the University of Bergen is currently overseeing clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as a possible treatment for Parkinson’s patients. In a recent presentation, Dr. Tzoulis explained why he chose to use NR as opposed to any other NAD+ precursor:

Parkinson’s Expert Explains Why He’s Aggressively Testing Nicotinamide Riboside in Parkinson’s Patients

Earlier this week, Ladenburg Thalmann, a US investment firm hosted a Healthcare Symposia. One of its guest speakers was Dr. Charalampos (Haris) Tzoulis, Professor of Neurology and Neurodegeneration at the University of Bergen and Haukeland University Hospital, Bergen Norway. Dr. Tzoulis recently completed a Phase 1 clinical trial testing vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) in Parkinson’s patients. Here’s how Dr. Tzoulis explained why he initiated the study:

Can Nicotinamide Riboside (NR) Help with Myocarditis?

Earlier today, Dr. Charles Brenner (FAQs) was asked whether NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) might help those suffering from Myocarditis (which occurs when the heart muscle becomes inflamed). Here’s his response:

What Does One of the Top Alzheimer’s Researchers Think about the Latest Alzheimer’s Study Including Nicotinamide Riboside “NR”?

Last week, results of a clinical study were released bringing new hope for Alzheimer’s patients: “Our results indicate that treatment of AD patients with CMA (full list) can lead to enhanced cognitive functions and improved clinical parameters associated with phenomics, metabolomics, proteomics and imaging analysis.” While this is clearly encouraging news, we’re quick to defer to the expertise of those better positioned to analyze the study results to tell us what they mean. And there’s no one better than Alzheimer’s expert Dr. Rudy Tanzi — who also happens to be a passionate consumer of one of the CMAs in the latest study, Nicotinamide Riboside “NR” (FAQs) (Reviews).

Middle-Aged Rich Guy Wants To Be 18 Again; How Did NR Make His List of Daily Supplements?

You’ve probably read about 45-year-old Bryan Johnson (Bloomberg: How to Be 18 Years Old Again for Only $2 Million a Year). He sold a company to eBay and is now taking extreme measures to try to be physically and mentally 18 again. Among the 24 supplements he takes each day is NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes):

Can Nicotinamide Riboside (NR) Slow the Decline of the Oocyte Reserve?

We recently heard from an excellent new site, “Science of NAD”, that “numerous mouse studies show that NAD replenishment can protect oocytes“. And here at RaisingNAD, we’ve compiled compelling evidence from experts and consumers that NAD+ boosters, Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) might possibly help those struggling with fertility by improving egg quality. See HERE. So, where does that leave us? When will we know whether the results of these mouse studies are a viable, evidence-based treatment option for humans? Fortunately, earlier this week, NAD+ expert Dr. Charles Brenner (FAQs) was asked about this very issue on Twitter:

Will the Proposed NMN Drug Have the Same NMN as NMN the Supplement?

With the announcement of a proposed NMN drug, and the possible permanent ban on NMN supplements, consumers are obviously confused. One thing we do know is the type of NMN to be included in the proposed drug:

Does NAD+ Supplement Nicotinamide Riboside “NR” Impair Muscle Performance?

A few days ago, Dr. Charles Brenner (FAQs) was asked whether consuming NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) risked impairing workout muscle performance. Here’s his response:

The Kardashian Conundrum: Which NAD Horse to Back? NMN, NR, or NAD+ IVs?

If the Kardashians are interested, one can assume they smell opportunity. That appears to be the case with NAD+. Last year, Kourtney K. touted NR. She now appears to have soured on NR, and is currently embracing NMN. Separately, her sister Kendall loves NAD+ IVs. Are these science based decisions?

Which NAD+ Supplement Does Dr. Andrew Huberman Take? NMN or NR?

Earlier this week, Stanford neuroscientist Dr. Andrew Huberman (FAQs) published an exhaustive podcast on health supplements entitled “Developing a Rational Approach to Supplementation for Health & Performance“. But there was one glaring omission. He didn’t address NAD+ supplements NMN (FAQs and Anecdotes) and Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Should this be surprising? Well, yes, considering that in a previous episode with Dr. David Sinclair, Huberman declared his intention to start taking NMN. Fortunately, we have this from Twitter:

When Can We Expect NMN as a Drug?

If NAD+ boosting supplement NMN (FAQs and Anecdotes) is permanently banned, when can consumers anticipate the arrival of NMN the drug? Dr. David Sinclair shared the following in a recent podcast interview with Dr. Peter H. Diamandis:

Will NAD+ Supplement NMN Be Permanently Banned?

Following a recent FDA determination, many consumers are concerned about the future availability of NAD+ boosting supplement NMN (FAQs and Anecdotes). While these concerns appear warranted, Dr. David Sinclair sought to reassure NMN supplement consumers in a Tweetstorm at the end of December (see below):

Half-a-Dozen Studies Now Show that Raising NAD Levels Improves Fertility by Increasing Oocyte Quality

There’s a growing belief that NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) might play a role in improving fertility chances. We’ve compiled the opinions of fertility specialists, NAD+ experts, as well as a number of real-life consumer anecdotes HERE. To bolster the case, “Science of NAD” recently published an exhaustive look at the scientific evidence supporting the connection between higher NAD+ levels and fertility. Here’s their conclusion:

What Does Dr. Charles Brenner Feel From Taking Supplement Nicotinamide Riboside “NR”?

We’ve long known what Dr. David Sinclair says he feels from taking NAD+ booster NMN (FAQs and Anecdotes). Now we know what Dr. Charles Brenner (FAQs) believes he experiences from taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). From last week’s “Making Sense of Science” podcast:

In His Latest Podcast Appearance, Dr. Brenner Addressed the NR/Cancer Connection

There’s been a lot of confusion lately regarding the possible connection between NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) and cancer. You can read more HERE. Fortunately, this past week, Matt Fuchs, editor-in-chief of Leaps.org asked NAD+ expert Dr. Charles Brenner (FAQs) about the issue during the “Making Sense of Science” podcast. Key quotes and podcast embedded below:

Is Nicotinamide Riboside “NR” More Useful than Niacin?

Last week, NAD+ expert Dr. Charles Brenner (FAQs) was asked whether NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) might be more useful than Niacin. Here’s what he said:

At What Age Should You Consider Taking Nicotinamide Riboside “NR”?

Dr. Charles Brenner (FAQs) is often asked when is the right time to start taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). His answer to this question in a Twitter exchange yesterday likely explains why some professional sports teams including the New England Patriots, Kansas City Chiefs, Tampa Bay Buccaneers, and New York Yankees are reportedly frequent consumers:

Does Niacinamide (Nicotinamide) Raise NAD+ Levels?

On Twitter yesterday, Dr. Bill Lagakos asked NAD+ expert Dr. Charles Brenner (FAQs) whether Niacinamide (also known as Nicotinamide) raises NAD+ levels. Here’s what he said:

New NMN Products for Cats and Dogs

We’ve heard repeatedly from pet owners sharing testimonials and offering dosage advice after feeding NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) to their cats and dogs. We’ve also heard from a pet owner sharing a remarkable story of what she believes NAD+ boosting supplement NMN (FAQs and Anecdotes) did for her cat. You can read a one-page summary of all of this HERE. Now comes new NMN products specifically for cats and dogs.

Who Takes Vitamin Supplement Nicotinamide Riboside “NR”? Our Growing List

Once you decide to take an NAD+ boosting supplement, the next big challenge is deciding which one. The following is a list of people who take Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). Perhaps this list will help you. We’ll continue to update it regularly:

Jessica Alba’s Trainer Recommends Boosting NAD+ Levels

While we typically avoid sharing articles about people who are compensated for recommending NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes), we’re doing so here to highlight how Jessica Alba’s trainer explains NAD+ and the case for supplementation. From “The Chalk Board (A Guide to Living Well)“:

Long COVID ‘Brain Fog’ an Increasing Concern; Nicotinamide Riboside Being Tested as Possible Treatment

An article this past weekend in the Toronto Sun claims that “Brain fog”, a typical symptom of long COVID, is currently a major concern for both scientists and sufferers alike. One possible treatment being tested is NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). Key quote:

What’s NAD+ (N.A.D.)?

You’ve likely heard of NAD+ (N.A.D.). But what is it? And why should you care? The following is a roundup of articles we’ve written over the last few years that we hope helps explain it:

On Dr. Attia’s Podcast, Princeton’s Dr. Rabinowitz Said the Body Barely Sees Vitamin Supplement Nicotinamide Riboside “NR”. Is He Wrong?

Those who question the efficacy of NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) often point to the work of Princeton’s Dr. Joshua Rabinowitz. Here’s a clip of Dr. Rabinowitz in an appearance on Dr. Peter Attia’s podcast explaining his reasoning followed by a response from NAD+ and NR expert Dr. Charles Brenner:

Anecdote #30: After Taking Vitamin Supplement NR for 2 Years, “Phil L.” Shares How His Life Has Noticeably Changed

While we await more conclusive evidence from clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), we have the luxury of consumers sharing their own personal experiences here at RaisingNAD. You can see the full alphabetical list of diseases and conditions impacted here. The latest consumer submitted anecdote comes from Phil L. who resides in Honolulu, Hawaii (please consider sharing your own experience below):

FAQs on NAD+ Supplements (NR, NMN) and Cancer

Do NAD+ supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) promote cancer growth? Well, despite their various disagreements, this is one issue NAD+ experts Dr. David Sinclair and Dr. Charles Brenner appear to agree on in regards to their favorite NAD+ boosting supplements:

Do Nicotinamide and Niacin Provide Protection Against Cancer?

Earlier today on Twitter, NAD+ and NR expert Dr. Charles Brenner was asked whether Nicotinamide and Nicotinic Acid (Niacin) provide protection against cancer. Here’s what he said:

Dr. Hoffman on the NR / Cancer Debate: “I’m Going to Keep Taking it, Keep Recommending it (NR)”

During his Intelligent Medicine Podcast earlier today, Dr. Ronald Hoffman MD addressed “a flurry of listener questions” about Nicotinamide Riboside “NR” (FAQs) (Reviews) and cancer. These questions were in response to this week’s news article entitled “Popular Dietary Supplement Causes Cancer Risk and Brain Metastasis” which we covered here. Here are key quotes from Dr. Hoffman (podcast embedded below):

Is Beer a Great Source of Nicotinamide Riboside “NR”?

During the latest “Reason with Science” podcast, NAD+ expert Dr. Charles Brenner (FAQs) discussed the many sources of NAD+ in our food supply. Here’s what he said about beer and NAD+ boosting vitamin Nicotinamide Riboside “NR” (FAQs) (Reviews):

FAQs on Dr. Charles Brenner — Leading Authority on NAD+ and Nicotinamide Riboside “NR”

As the popularity of NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) grows, so do the number of consumer questions. To answer many of these questions, we have the luxury of turning to Dr. Charles Brenner who discovered NR as an NAD+ boosting vitamin and who often shares his scientific, evidence-based opinions on various podcasts:

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