During this week’s Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked about NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) vs NMN (FAQs). Here’s the Redditor’s question followed by Brenner’s response:

REDDIT Question:

Hi Dr Brenner. Thanks for this. From what I understand NMN and NR are equally effective. Is there a solid argument for one or the other?

DR. CHARLES BRENNER:

there’s much less human research with NMN

there’s not a known safe source for NMN

NMN doesn’t get into cells as NMN. it gets in as NR and there’s a safe source of NR so why are we still talking about NMN?

REDDIT Question:

More research is coming out though, no? I’m currently taking both NR and NMN. Can you expand on what you mean by no known safe source? The tests show my supps as pure NR and pure Nmn. Bryan Johnson took both and says they’re equally effective for raising nad.

DR. CHARLES BRENNER:

the F in FDA stands for food and it governs both food an new dietary ingredients

the DSHEA law states that if a substance has entered testing as a drug, it cannot be permitted as a dietary ingredient. Metro Biotech notified FDA that they have been testing NMN as a drug. FDA then told everyone that it cannot be a dietary ingredient

if you are buying NMN as a dietary ingredient, you are dealing with a company that is selling it in the face of a ruling by the US agency trying to keep dietary ingredients safe

Related:

  • Reddit AMA: Dr. Brenner Responds to Qs about Why Take NR (Link)
  • Reddit AMA: Dr. Brenner Responds to Qs about NR & Cancer (Link)
  • Reddit AMA: Dr. Brenner Responds to Qs on NR/NMN Trials (Link)
  • Reddit AMA: Dr. Brenner Responds to Qs about NR & Diabetes (Link)
  • Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes)
  • Nicotinamide Mononucleotide “NMN” (FAQs and Anecdotes)

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