During an ongoing Reddit AMA (“Ask Me Anything”) taking place on the NR subreddit, NAD+ expert Dr. Charles Brenner (FAQs) was asked a series of questions about NMN (FAQs and Anecdotes). While we know that his preferred NAD+ booster is vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes), he offered the following for all those looking to make an NMN purchase:
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During last week’s Huberman Lab podcast with Dr. Peter Attia, Dr. Andrew Huberman (FAQs) shared his current regimen of NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes). Here’s what he said:
A few years ago, a surprising study showed that a large majority of the top 22 NMN brands sold on Amazon contained much less NMN than advertised (Link). Fast forward to mid-2024, a new study has found similar results (and only one NMN brand from the two studies overlapped). Here’s more from the 2024 NMN study:
While admittedly not an NAD+ expert, Stanford neuroscientist Dr. Andrew Huberman is very interested in the NAD+ space. He currently takes NR (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes). Here’s what he said on an AMA yesterday (key points in bold, summary at the end):
During an ongoing Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked about clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Again, keep in mind that Dr. Brenner takes NR daily. Here’s the Redditor’s question followed by Brenner’s response:
Last week, Dr. Andrew Salzman joined “The Doctor’s Farmacy with Mark Hyman M.D.” to discuss NAD+, NR (FAQs), and NMN (FAQs). Dr. Salzman made the case that if you want to raise your NAD+ levels, NMN is your best option. There are 2 problems here. First, neither Dr. Salzman nor Dr. Hyman disclosed Salzman’s ties to a company that sells NMN. Second, according to Dr. Charles Brenner (FAQs), Dr. Salzman’s case for NMN’s superiority is flawed. Brenner knows this from his own work. But, first, here’s Dr. Salzman on Dr. Hyman’s podcast:
During last week’s appearance on the “World of DaaS” podcast (transcript and video below), Harvard’s Dr. David Sinclair made a compelling case for all NAD+ boosters. We know he’s a proponent of taking NAD+ booster NMN (FAQs, Anecdotes). But in this latest podcast, Sinclair appears to acknowledge more broadly that “NAD boosters, as they’re called, seem to be really beneficial”. So, if you recognize that Sinclair’s previous arguments in favor of NMN over NR are less than compelling (including an incorrect statement about NR stability), and you’re wondering what to do following the FDA’s recent NMN ban, Sinclair appears to be telling you that other NAD boosters are also worthwhile:
In a 2020 podcast, Harvard’s Dr. David Sinclair explained why he took (and continues to take) NAD+ boosting supplement NMN (FAQs and Anecdotes) over fellow NAD+ booster NR (FAQs) (Anecdotes). One of his reasons was that NMN was more stable. Is this in fact true?
Last week, Harvard’s Dr. David Sinclair (FAQs) was interviewed at the Time 100 Most Influential People 2023 Summit. He discussed his personal health regimen including taking NAD+ boosting supplement NMN (FAQs, Anecdotes). Key quotes (video embedded below):
On at least three occasions (Anecdote #3) (#7) (#28), we’ve heard from consumers reporting that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) provided some relief from Restless Legs Syndrome (RLS). Now comes NMN (FAQs, Anecdotes) consumer Ken Osborn with a similar story (submitted via our online form, and confirmed via email):
In a video this week, Marcel at The Pulse explained why he takes NAD+ booster NMN (FAQs, Anecdotes) over NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Here’s what he said (video embedded below):
As is typical of the NAD+ supplement space, there’s enormous confusion around the FDA’s recent ban of NAD+ boosting supplement NMN. Long time NMN consumers are obviously concerned that their NAD+ booster of choice might soon be unavailable. What are some of the key players in the NAD+ supplement space saying about the path forward? Here are key quotes from Harvard’s Dr. David Sinclair (FAQs), Stanford’s Dr. Andrew Huberman (FAQs), and City of Hope’s Dr. Charles Brenner (FAQs):
Many people turn to Stanford neuroscientist Dr. Andrew Huberman (FAQs) for advice on various health related topics including NAD boosting supplements NMN (FAQs, Anecdotes) and NR (FAQs) (Anecdotes). Here’s an update he gave a few days ago:
Last week, Stanford neuroscientist Dr. Andrew Huberman (FAQs) spent much of his appearance on the Joe Rogan podcast explaining the FDA’s recent ban of NAD+ boosting supplement NMN (FAQs, Anecdotes). Dr. David Sinclair recently tweeted about the ban HERE. And, here’s Dr. Huberman explaining the situation to Joe Rogan:
While admittedly not an NAD+ expert, Stanford neuroscientist Dr. Andrew Huberman is very interested in the NAD+ space. He currently takes NMN (FAQs and Anecdotes). And since he has a wealth of knowledge, access to NAD experts, and a huge platform, we’re keeping track of his latest comments. Here’s what he’s recently said:
On two occasions we’re aware of, Stanford neuroscientist Dr. Andrew Huberman (FAQs) has discussed his experience taking NAD+ boosting supplement NMN (FAQs and Anecdotes). The first time was on Twitter. The second time was on the Joe Rogan podcast. You can see both below:
Here’s what Stanford neuroscientist Dr. Andrew Huberman (FAQs) told podcaster Joe Rogan last week in explaining why he takes NAD+ boosting supplement NMN (FAQs and Anecdotes), and also believes in fellow NAD+ booster NR (FAQs) (Anecdotes):
NAD+ expert Dr. Charles Brenner (FAQs) often says that NAD+ boosting supplement NMN (FAQs and Anecdotes) doesn’t enter cells. What’s his proof? Take a look:
Stanford neuroscientist, Dr. Andrew Huberman (FAQs) was a guest on the Joe Rogan podcast yesterday. Here’s what he said about NAD+ boosting supplement NMN (FAQs, Anecdotes):
During last night’s quarterly earnings call, a fund manager asked Chromadex CEO Rob Fried about the efficacy of NMN (FAQs, Anecdotes). NMN is, of course, an NAD+ boosting supplement that competes with Chromadex’s NAD+ booster Nicotinamide Riboside (FAQs + Dosage) (Life-Changing Anecdotes). Here’s what CEO Fried said in response:
At RaisingNAD, we have limited science background. So, this site is devoted to helping other non-scientists quickly understand the complex and confusing world of NAD+ health supplements like NMN and NR. Please consider sharing this site with anyone you think might find it useful. And, if this site helps you, and you’d like to support our efforts, please contact us. We’d be grateful. The following are our most popular blog posts:
With the announcement of a proposed NMN drug, and the possible permanent ban on NMN supplements, consumers are obviously confused. One thing we do know is the type of NMN to be included in the proposed drug:
If the Kardashians are interested, one can assume they smell opportunity. That appears to be the case with NAD+. Last year, Kourtney K. touted NR. She now appears to have soured on NR, and is currently embracing NMN. Separately, her sister Kendall loves NAD+ IVs. Are these science based decisions?
Earlier this week, Stanford neuroscientist Dr. Andrew Huberman (FAQs) published an exhaustive podcast on health supplements entitled “Developing a Rational Approach to Supplementation for Health & Performance“. But there was one glaring omission. He didn’t address NAD+ supplements NMN (FAQs and Anecdotes) and Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Should this be surprising? Well, yes, considering that in a previous episode with Dr. David Sinclair, Huberman declared his intention to start taking NMN. Fortunately, we have this from Twitter:
If NAD+ boosting supplement NMN (FAQs and Anecdotes) is permanently banned, when can consumers anticipate the arrival of NMN the drug? Dr. David Sinclair shared the following in a recent podcast interview with Dr. Peter H. Diamandis:
Following a recent FDA determination, many consumers are concerned about the future availability of NAD+ boosting supplement NMN (FAQs and Anecdotes). While these concerns appear warranted, Dr. David Sinclair sought to reassure NMN supplement consumers in a Tweetstorm at the end of December (see below):
We’ve heard repeatedly from pet owners sharing testimonials and offering dosage advice after feeding NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) to their cats and dogs. We’ve also heard from a pet owner sharing a remarkable story of what she believes NAD+ boosting supplement NMN (FAQs and Anecdotes) did for her cat. You can read a one-page summary of all of this HERE. Now comes new NMN products specifically for cats and dogs.
Do NAD+ supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) promote cancer growth? Well, despite their various disagreements, this is one issue NAD+ experts Dr. David Sinclair and Dr. Charles Brenner appear to agree on in regards to their favorite NAD+ boosting supplements:
We’ve heard some inspiring stories from consumers taking matters into their own hands and feeding their cats and dogs NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (Pet Anecdotes). Now comes Jackie with an equally remarkable story about the impact she believes NAD+ supplement NMN had on her ailing cat (please consider sharing your own NAD+ supplement experience using the form below):
Rather than deciding between NAD+ boosting supplements NMN (FAQs and Anecdotes) and NR (FAQs) (Anecdotes), some consumers take NAD+. NAD+ expert Dr. Charles Brenner explains why that doesn’t make sense to him (video and transcript below):
In late 2019, NAD+ expert Dr. Charles Brenner received a research grant from the Gates Foundation to study the various NAD+ precursors including NMN (FAQs and Anecdotes) and NR (FAQs) (Anecdotes). This past week, Dr. Brenner finally provided a peek at what he found (videos and transcripts below):
Earlier today, a caller asked Dr. Drew for his thoughts on NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) (Podcasts). Here’s what he said in response about NR and NMN (FAQs and Anecdotes) (video and transcript below):
Here’s what we’ve learned after 2 years of writing this site. Choosing an NAD+ boosting vitamin supplement is difficult. Do you take NMN (FAQs and Anecdotes) or NR (FAQs) (Anecdotes)? And once you decide between the two, which of the many sellers do you purchase from? We know that NMN is by far the more popular. But many red flags suggest caution. Scientists warn about it and many NMN sellers don’t sell what they say they do. This suggests that there’s no standard NMN product. Everyone is selling something different. It’s quite astonishing then that so many consumers choose to purchase and ingest NMN in large numbers. This commercial miracle is likely in large part due to the support of Harvard’s Dr. David Sinclair (though, to add to the confusion, he doesn’t tell you where he gets his NMN from and doesn’t endorse any specific NMN brand). So where does that leave potential consumers looking for guidance on which supplement to buy and where to buy it from? The following are the top 10 blog posts that readers of this site have found most useful in their quest for answers. Hopefully you’ll find them useful too:
We’re always on the lookout for podcasts where experts make the case for taking NAD+ boosting vitamin supplements like Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes), or getting NAD+ IV drips (FAQs). The challenge is finding podcasts that explain these complex topics in ways easily accessible to the general public. Below is our growing list. If you’re aware of others, we’d be delighted to include them:
As a result of this paper, many believe there’s a transporter that carries NAD+ booster NMN (FAQs and Anecdotes) into cells. Dr. Charles Brenner, who discovered Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as an NAD+ booster vitamin says the notion of the existence of a transporter is mistaken. Below, he makes the case:
As people learn more about the importance of elevating NAD+ levels to improve health by taking supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes), NMN (FAQs and Anecdotes), or getting NAD+ IV drips (FAQs), many questions inevitably follow. Here are links to blog posts answering many of your pressing questions:
On a recent podcast, Harvard’s Dr. David Sinclair was asked about concerns that NAD boosting supplement NMN (FAQs & Anecdotes) causes cancer growth. Here’s what he said:
During this week’s Huberman Lab Podcast, Harvard’s Dr. David Sinclair was asked what to expect from taking NAD+ boosting supplement NMN (FAQs and Anecdotes). Here’s what he said (please consider sharing your own NAD+ supplement experience using the submission form below):
On his most recent Huberman Lab Podcast, Stanford neuroscientist Andrew Huberman (FAQs) told Dr. David Sinclair about his sister’s experience taking NAD+ boosting supplement NMN (FAQs and Anecdotes) (please consider sharing your own NAD+ supplement experience using the form below):
We’ve previously heard from a Harvard trained fertility specialist who recommends NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) to patients looking to improve egg quality. We’ve also heard anecdotal evidence from people struggling with fertility that NR might be a treatment solution (“Our Niagen Baby“). Now comes Harvard’s Dr. David Sinclair on a podcast earlier this week claiming he too believes that NAD boosting supplements (in this case, NMN (FAQs and Anecdotes)) may help aspiring parents (video embedded below):
How do you decide which NMN (FAQs and Anecdotes) brand to take? If you’re struggling with this question, you’re not alone. Many consumers take NAD boosting supplement NMN on the advice of Harvard’s Dr. David Sinclair. Unfortunately, Dr. Sinclair doesn’t endorse any specific NMN brand. So, consumers are on their own to determine which of the hundreds of NMN brands to purchase. The only advice Dr. Sinclair provides is that when you’re evaluating NMN brands “you want to look for good manufacturing practices, GMP grade, high quality and trusted manufacturers“. Is the average consumer properly equipped to make such a determination on his or her own? Well, thanks to a new report, we now have some visibility into the immense challenge consumers face in identifying safe and reliable NMN brands:
Below is an excerpt from a conversation between Harvard’s Dr. David Sinclair and Stanford neuroscientist Andrew Huberman where Sinclair is asked what NMN (FAQs and Anecdotes) brand he recommends:
If you’ve decided to take supplement NMN (FAQs and Anecdotes) over Nicotinamide Riboside “NR” (FAQs) (Anecdotes), Dr David Sinclair has some advice for you. While we’ve never seen him recommend a specific NMN brand, he periodically offers dosage advice. He posted the following this past weekend on Twitter:
Last week, we wrote a blog post about the supplement NMN (FAQs and Anecdotes) entitled “If NMN is Safe, Why Don’t Regulators Approve It?“. We were subsequently made aware of an article by a group of scientists published last month in the Journal of Advanced Research entitled “Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns“. It raises serious concerns about the safety of NMN. The following are the authors’ conclusions:
Much to my surprise, lots of people take NAD+ boosting supplement NMN (FAQs and Anecdotes). But as readers of this site know, I’m certainly not one of them. While I’m sold on the importance of boosting NAD+ levels, I defer to the regulatory authorities in charge of evaluating consumer safety to determine which NAD booster to take. And hands down, it’s Nicotinamide Riboside “NR” (FAQs) (Anecdotes). It’s not even close. NR has been deemed safe by the FDA (NDI), Health Canada, EFSA, Australian TGA, and achieved GRAS status — NMN has received none of these approvals. What about the general science community? Well, they’ve clearly made their choice, too. There are currently 67 human clinical trials at some stage testing NR as a treatment for various diseases — only 14 trials for NMN. This suggests that scientists overwhelming choose NR when testing NAD boosters on human subjects. As well, the scientists at Nestlé chose NR over NMN when launching new food and beverage products selling to the general population. But while NR appears the safe choice, it remains abundantly concerning that even with the lack of regulatory body safety recognition, there’s obviously so much consumer demand for NMN that there are MANY companies still selling it. And each of these companies is selling something different. So it’s virtually impossible to know what you’re actually ingesting when taking NMN. And yet NMN remains incredibly popular. It’s a marketing triumph of significant proportions that so many consumers have been convinced to put something in their bodies that has so many red flags in plain sight. And then comes this: