Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Tag: NMN

Reddit AMA: Dr. Brenner Responds to Questions about NR, NMN Clinical Trials

During an ongoing Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked about clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Again, keep in mind that Dr. Brenner takes NR daily. Here’s the Redditor’s question followed by Brenner’s response:

The Flawed Case for NMN

Last week, Dr. Andrew Salzman joined “The Doctor’s Farmacy with Mark Hyman M.D.” to discuss NAD+, NR (FAQs), and NMN (FAQs). Dr. Salzman made the case that if you want to raise your NAD+ levels, NMN is your best option. There are 2 problems here. First, neither Dr. Salzman nor Dr. Hyman disclosed Salzman’s ties to a company that sells NMN. Second, according to Dr. Charles Brenner (FAQs), Dr. Salzman’s case for NMN’s superiority is flawed. Brenner knows this from his own work. But, first, here’s Dr. Salzman on Dr. Hyman’s podcast:

In Latest Podcast, Dr. David Sinclair Makes the Case for All NAD+ Boosters

During last week’s appearance on the “World of DaaS” podcast (transcript and video below), Harvard’s Dr. David Sinclair made a compelling case for all NAD+ boosters. We know he’s a proponent of taking NAD+ booster NMN (FAQs, Anecdotes). But in this latest podcast, Sinclair appears to acknowledge more broadly that “NAD boosters, as they’re called, seem to be really beneficial”. So, if you recognize that Sinclair’s previous arguments in favor of NMN over NR are less than compelling (including an incorrect statement about NR stability), and you’re wondering what to do following the FDA’s recent NMN ban, Sinclair appears to be telling you that other NAD boosters are also worthwhile:

Dr. Sinclair Done with Alcohol. Resveratrol Too?

Since this site is devoted to covering NAD+ boosters NR (FAQs) (Anecdotes) and NMN (FAQs, Anecdotes), we closely follow the work of Dr. David Sinclair. As a result, we periodically take note of his and various critics’ comments on Resveratrol. During a panel discussion at the Milken Institute Global Conference yesterday entitled “Hacking Aging: The Quest for Longevity”, Sinclair made the following comments (video embedded below):

At “Time 100”, Dr. Sinclair Discussed His Personal Health Regimen Including NMN

Last week, Harvard’s Dr. David Sinclair (FAQs) was interviewed at the Time 100 Most Influential People 2023 Summit. He discussed his personal health regimen including taking NAD+ boosting supplement NMN (FAQs, Anecdotes). Key quotes (video embedded below):

First, NR. Now, NMN. Another Consumer Reports NAD+ Booster Provided Relief from Restless Legs Syndrome RLS

On at least three occasions (Anecdote #3) (#7) (#28), we’ve heard from consumers reporting that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) provided some relief from Restless Legs Syndrome (RLS). Now comes NMN (FAQs, Anecdotes) consumer Ken Osborn with a similar story (submitted via our online form, and confirmed via email):

Why Does YouTube Channel “The Pulse” Take NMN over NR?

In a video this week, Marcel at The Pulse explained why he takes NAD+ booster NMN (FAQs, Anecdotes) over NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Here’s what he said (video embedded below):

Drs. Sinclair, Huberman, and Brenner on the Future of NMN After the FDA Ban

As is typical of the NAD+ supplement space, there’s enormous confusion around the FDA’s recent ban of NAD+ boosting supplement NMN. Long time NMN consumers are obviously concerned that their NAD+ booster of choice might soon be unavailable. What are some of the key players in the NAD+ supplement space saying about the path forward? Here are key quotes from Harvard’s Dr. David Sinclair (FAQs), Stanford’s Dr. Andrew Huberman (FAQs), and City of Hope’s Dr. Charles Brenner (FAQs):

For Dr. Andrew Huberman, Choosing an NAD Supplement Comes Down to Cost

Many people turn to Stanford neuroscientist Dr. Andrew Huberman (FAQs) for advice on various health related topics including NAD boosting supplements NMN (FAQs, Anecdotes) and NR (FAQs) (Anecdotes). Here’s an update he gave a few days ago:

Dr. Huberman Explains the FDA’s NMN Ban

Last week, Stanford neuroscientist Dr. Andrew Huberman (FAQs) spent much of his appearance on the Joe Rogan podcast explaining the FDA’s recent ban of NAD+ boosting supplement NMN (FAQs, Anecdotes). Dr. David Sinclair recently tweeted about the ban HERE. And, here’s Dr. Huberman explaining the situation to Joe Rogan:

FAQs on Dr. Andrew Huberman — His Thoughts on NMN and NR

While admittedly not an NAD+ expert, Stanford neuroscientist Dr. Andrew Huberman is very interested in the NAD+ space. He currently takes NMN (FAQs and Anecdotes). And since he has a wealth of knowledge, access to NAD experts, and a huge platform, we’re keeping track of his latest comments. Here’s what he’s recently said:

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What Does Dr. Huberman Feel After Taking NMN?

On two occasions we’re aware of, Stanford neuroscientist Dr. Andrew Huberman (FAQs) has discussed his experience taking NAD+ boosting supplement NMN (FAQs and Anecdotes). The first time was on Twitter. The second time was on the Joe Rogan podcast. You can see both below:

Dr. Huberman Believes in NAD+ Boosters NR and NMN

Here’s what Stanford neuroscientist Dr. Andrew Huberman (FAQs) told podcaster Joe Rogan last week in explaining why he takes NAD+ boosting supplement NMN (FAQs and Anecdotes), and also believes in fellow NAD+ booster NR (FAQs) (Anecdotes):

Is There Definitive Proof NMN Doesn’t Enter Cells?

NAD+ expert Dr. Charles Brenner (FAQs) often says that NAD+ boosting supplement NMN (FAQs and Anecdotes) doesn’t enter cells. What’s his proof? Take a look:

Dr. Andrew Huberman to Joe Rogan: “I Think That Keeping NMN on the Market as a Supplement Would Be Wonderful”

Stanford neuroscientist, Dr. Andrew Huberman (FAQs) was a guest on the Joe Rogan podcast yesterday. Here’s what he said about NAD+ boosting supplement NMN (FAQs, Anecdotes):

Frequently Asked Questions (FAQs) and Anecdotes on Nicotinamide Mononucleotide “NMN”

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Though it’s increasingly difficult to purchase NAD+ boosting supplement Nicotinamide Mononucleotide “NMN” (versus other NAD+ precursors like Nicotinamide Riboside “NR” (FAQs) (Anecdotes)), you might find the following useful:

You Might Be Surprised to Hear How NR Seller Chromadex Described Competitor NMN During Last Night’s Earnings Call

During last night’s quarterly earnings call, a fund manager asked Chromadex CEO Rob Fried about the efficacy of NMN (FAQs, Anecdotes). NMN is, of course, an NAD+ boosting supplement that competes with Chromadex’s NAD+ booster Nicotinamide Riboside (FAQs + Dosage) (Life-Changing Anecdotes). Here’s what CEO Fried said in response:

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At RaisingNAD, we have limited science background. So, this site is devoted to helping other non-scientists quickly understand the complex and confusing world of NAD+ health supplements like NMN and NR. Please consider sharing this site with anyone you think might find it useful. And, if this site helps you, and you’d like to support our efforts, please contact us. We’d be grateful. The following are our most popular blog posts:

Expert: “We Think that Higher NAD Status is Really Important for Prevention of Cancer”

During an interview earlier this week, NAD+ expert, Dr. Charles Brenner (FAQs) was asked whether daily consumption of vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) brought cancer risk. Here’s what he said:

What Does NAD+ Expert Dr. Charles Brenner Eat for Breakfast along with his Nicotinamide Riboside (NR)?

If you watch interviews with NMN expert Dr. David Sinclair, you’ll find he often discusses his breakfast routine (see below). What about NR expert Dr. Charles Brenner (FAQs)? Well, typically, his mantra on breakfast is “you do you”. But, earlier this week, we finally got more details.

FAQs on the Potential for Nicotinamide Riboside (NR) in Parkinson’s Patients

Parkinson’s expert Dr. Charalampos (Haris) Tzoulis is actively running clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a possible treatment option for Parkinson’s patients. He’s clearly optimistic. And, as you’ll see below, this is consistent with what we’ve heard from NAD+ experts Dr. Charles Brenner (FAQs) and Dr. David Sinclair in regards to their preferred NAD+ precursors, NR and NMN, respectively:

Can Nicotinamide Riboside (NR) Slow the Decline of the Oocyte Reserve?

We recently heard from an excellent new site, “Science of NAD”, that “numerous mouse studies show that NAD replenishment can protect oocytes“. And here at RaisingNAD, we’ve compiled compelling evidence from experts and consumers that NAD+ boosters, Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) might possibly help those struggling with fertility by improving egg quality. See HERE. So, where does that leave us? When will we know whether the results of these mouse studies are a viable, evidence-based treatment option for humans? Fortunately, earlier this week, NAD+ expert Dr. Charles Brenner (FAQs) was asked about this very issue on Twitter:

    The Kardashian Conundrum: Which NAD Horse to Back? NMN, NR, or NAD+ IVs?

    If the Kardashians are interested, one can assume they smell opportunity. That appears to be the case with NAD+. Last year, Kourtney K. touted NR. She now appears to have soured on NR, and is currently embracing NMN. Separately, her sister Kendall loves NAD+ IVs. Are these science based decisions?

    Which NAD+ Supplement Does Dr. Andrew Huberman Take? NMN or NR?

    Earlier this week, Stanford neuroscientist Dr. Andrew Huberman (FAQs) published an exhaustive podcast on health supplements entitled “Developing a Rational Approach to Supplementation for Health & Performance“. But there was one glaring omission. He didn’t address NAD+ supplements NMN (FAQs and Anecdotes) and Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Should this be surprising? Well, yes, considering that in a previous episode with Dr. David Sinclair, Huberman declared his intention to start taking NMN. Fortunately, we have this from Twitter:

    When Can We Expect NMN as a Drug?

    If NAD+ boosting supplement NMN (FAQs and Anecdotes) is permanently banned, when can consumers anticipate the arrival of NMN the drug? Dr. David Sinclair shared the following in a recent podcast interview with Dr. Peter H. Diamandis:

    Will NAD+ Supplement NMN Be Permanently Banned?

    Following a recent FDA determination, many consumers are concerned about the future availability of NAD+ boosting supplement NMN (FAQs and Anecdotes). While these concerns appear warranted, Dr. David Sinclair sought to reassure NMN supplement consumers in a Tweetstorm at the end of December (see below):

    Half-a-Dozen Studies Now Show that Raising NAD Levels Improves Fertility by Increasing Oocyte Quality

    There’s a growing belief that NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) might play a role in improving fertility chances. We’ve compiled the opinions of fertility specialists, NAD+ experts, as well as a number of real-life consumer anecdotes HERE. To bolster the case, “Science of NAD” recently published an exhaustive look at the scientific evidence supporting the connection between higher NAD+ levels and fertility. Here’s their conclusion:

    New NMN Products for Cats and Dogs

    We’ve heard repeatedly from pet owners sharing testimonials and offering dosage advice after feeding NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) to their cats and dogs. We’ve also heard from a pet owner sharing a remarkable story of what she believes NAD+ boosting supplement NMN (FAQs and Anecdotes) did for her cat. You can read a one-page summary of all of this HERE. Now comes new NMN products specifically for cats and dogs.

    Which NAD+ Booster Performed Best in a Recent Head to Head Fully Blinded Study?

    In late 2019, NAD+ expert Dr. Charles Brenner received a research grant from the Gates Foundation to study the various NAD+ precursors including NMN (FAQs and Anecdotes) and NR (FAQs) (Anecdotes). This past week, Dr. Brenner finally provided a peek at what he found (videos and transcripts below):

    NAD+ in 3 Basic Slides

    You’re likely hearing more and more about NAD+. Nestlé has a new consumer brand focused on boosting NAD+ levels (more), the NFL’s New England Patriots consider NAD+ a daily essential (more), and, love them or hate them, even the Kardashians are now on board (more). So, what’s NAD+ and why does it matter to your health? Theses slides from a May 2022 investor presentation help quickly explain it:

    These Podcasts Help Explain NAD+ and Why It Matters

    We’re always on the lookout for podcasts where experts make the case for taking NAD+ boosting vitamin supplements like Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes), or getting NAD+ IV drips (FAQs). The challenge is finding podcasts that explain these complex topics in ways easily accessible to the general public. Below is our growing list. If you’re aware of others, we’d be delighted to include them:

    FAQs on Taking B3 Vitamin Supplements NR and NMN to Improve Fertility Chances

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    There’s increasing interest in NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs) (Reviews) and NMN (FAQs) as possible tools to help improve your chances of fertility. We hope the following blog posts are helpful in your journey:

    Can NAD Boosters Help Dogs? Dr. Sinclair’s Brother Launching One Soon

    Over the last year, we’ve heard from various people who believe their pets are benefiting from taking NAD boosting human vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). You can read their anecdotes here: (Cat) (Cat) (Dog). But is there an actual NAD booster for dogs on the way? Harvard’s Dr. David Sinclair explained on a recent podcast:

    What Does Dr. David Sinclair Feel After Taking NMN?

    During this week’s Huberman Lab Podcast, Harvard’s Dr. David Sinclair was asked what to expect from taking NAD+ boosting supplement NMN (FAQs and Anecdotes). Here’s what he said (please consider sharing your own NAD+ supplement experience using the submission form below):

    Stanford Neuroscientist Andrew Huberman on His Sister’s Experience Taking NMN

    On his most recent Huberman Lab Podcast, Stanford neuroscientist Andrew Huberman (FAQs) told Dr. David Sinclair about his sister’s experience taking NAD+ boosting supplement NMN (FAQs and Anecdotes) (please consider sharing your own NAD+ supplement experience using the form below):

    Dr. David Sinclair on NMN and Fertility: “You Can Rejuvenate the Female Reproductive System”

    We’ve previously heard from a Harvard trained fertility specialist who recommends NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) to patients looking to improve egg quality. We’ve also heard anecdotal evidence from people struggling with fertility that NR might be a treatment solution (“Our Niagen Baby“). Now comes Harvard’s Dr. David Sinclair on a podcast earlier this week claiming he too believes that NAD boosting supplements (in this case, NMN (FAQs and Anecdotes)) may help aspiring parents (video embedded below):

    Top 22 NMN Brands on Amazon Were Lab Tested for Potency; One Remarkable Takeaway

    How do you decide which NMN (FAQs and Anecdotes) brand to take? If you’re struggling with this question, you’re not alone. Many consumers take NAD boosting supplement NMN on the advice of Harvard’s Dr. David Sinclair. Unfortunately, Dr. Sinclair doesn’t endorse any specific NMN brand. So, consumers are on their own to determine which of the hundreds of NMN brands to purchase. The only advice Dr. Sinclair provides is that when you’re evaluating NMN brands “you want to look for good manufacturing practices, GMP grade, high quality and trusted manufacturers“. Is the average consumer properly equipped to make such a determination on his or her own? Well, thanks to a new report, we now have some visibility into the immense challenge consumers face in identifying safe and reliable NMN brands:

    Resveratrol + Nicotinamide Riboside (NR)? Another Scientist Says Evidence Doesn’t Support Popular Beliefs about Resveratrol

    Earlier this week, we explored whether taking a daily Resveratrol along with supplements Nicotinamide Riboside “NR” (FAQs) (Reviews) or NMN (FAQs) affords any health or longevity benefits. A former labmate of Dr David Sinclair says the answer is likely “no”. Now comes Dr Charles Brenner (NR and NAD expert) who agrees that “Resveratrol is hype”. He made the case on a recent podcast:

    Should You Take Resveratrol with Nicotinamide Riboside (NR)? Dr Sinclair’s Former Labmate Says Resveratrol Unlikely Impacts Health & Longevity

    There are often discussions online about taking a daily Resveratrol along with either Nicotinamide Riboside “NR” (FAQs) (Reviews) or NMN (FAQs). But should you follow this regimen? While Harvard’s Dr David Sinclair does (Resveratrol + NMN), his former labmate at MIT, Dr Matt Kaeberlein (who’s now a prominent scientist studying aging at the University of Washington) does not. He calls Resveratrol‘s impact on health and longevity likely a myth that unfortunately continues to dupe the public.

    How Much NMN Does Dr David Sinclair Take? What Dosage Does He Recommend?

    If you’ve decided to take supplement NMN (FAQs and Anecdotes) over Nicotinamide Riboside “NR” (FAQs) (Anecdotes), Dr David Sinclair has some advice for you. While we’ve never seen him recommend a specific NMN brand, he periodically offers dosage advice. He posted the following this past weekend on Twitter:

    Twitter Q&A with Dr Charles Brenner – NAD+ and Nicotinamide Riboside (NR) Expert

    Dr. Charles Brenner, University of Iowa professor and chief scientific advisor at Chromadex took questions from the public on Twitter today. He discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD boosting vitamin. Here’s the Q&A:

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