As you probably know, there’s a lot of Niacin in Western diets. So, when a new, potentially concerning Niacin study was published last week, the media sounded the alarm, and word spread quickly. Furthermore, those taking NAD+ boosters Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and/or Nicotinamide Mononucleotide “NMN” (FAQs and Anecdotes) began to wonder whether they, too, were at risk. But, as it turns out, there are some serious flaws in this whole narrative.
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We’ve written a lot about ongoing clinical trials testing NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) for Parkinson’s patients. Fortunately, Chromadex (NR sellers) CEO Rob Fried gave the following update on those trials at an investor conference earlier this week:
A common question consumers have is how much Nicotinamide Riboside “NR” (FAQs) (Anecdotes) to take daily. During an appearance on “The Story of a Brand” podcast, Chromadex (sellers of NR) CEO Rob Fried offered the following:
While obvious to some, many consumers often wonder whether the supplement they’re taking is positively impacting them. If the latter is you, you might find the following useful. During an appearance on “The Story of a Brand” podcast, Chromadex (sellers of NR) CEO Rob Fried had some advice for those taking vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and wondering if it’s working:
During his appearance on this week’s “The Story of a Brand” podcast, Chromadex (sellers of NR) CEO Rob Fried described his own experience taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Here’s what he said (podcast and transcript below):
Back in 2021, we profiled Harvard-trained fertility specialist Dr. Aimee Eyvazzadeh AKA “The Egg Whisperer”, and her experience with NAD+ boosting supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Now, in late 2023, Dr. Aimee appears even more enthusiastic. Here’s her recent appearance on the “Habits and Hustle” podcast (video and transcript below):
In a recent interview, Northwestern’s Dr. Mary McDermott discussed key findings from her team’s randomized clinical trial investigating whether NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes) can enhance walking performance in patients with peripheral artery disease (PAD). The results (using 1000 mg NR) showed that NR significantly improved six-minute walking distance and treadmill walking time in PAD patients. A transcript and video of Dr. McDermott’s interview below:
While we await data from clinical trials on the efficacy of NAD+ boosters like Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and Nicotinamide Mononucleotide “NMN” (FAQs and Anecdotes), we’re always on the lookout for comments from experts in the field to hear their current thinking. Earlier this week at an investor conference, Chromadex (NR seller) management had the following to say about NR for Parkinson’s patients (transcript and video below):
Once you’ve decided to supplement with NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes), you might wonder what dose to take. If that’s the case, you might find this post helpful. And what about the new 1000mg version from Chromadex? Here’s how management explained it on last week’s earnings call:
While consumers claim to have experienced a variety of life-changing benefits from taking NAD+ boosting supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes), NAD+ expert Charles Brenner (FAQs) says he takes it for the following reasons:
While admittedly not an NAD+ expert, Stanford neuroscientist Dr. Andrew Huberman is very interested in the NAD+ space. He currently takes NR (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes). Here’s what he said on an AMA yesterday (key points in bold, summary at the end):
During last week’s Neuro Experience podcast, NAD+ expert Dr. Charles Brenner (FAQs) made the case against NAD+ IVs. Here’s what he said (transcript and video below):
During an ongoing Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked about NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and diabetes. Here’s the Redditor’s question followed by Brenner’s response:
During an ongoing Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked about clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Again, keep in mind that Dr. Brenner takes NR daily. Here’s the Redditor’s question followed by Brenner’s response:
During an ongoing Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked repeatedly to make the case for taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Again, keep in mind that Dr. Brenner takes NR daily. Here’s the Redditors’ questions followed by Brenner’s responses:
During an ongoing Reddit AMA (Ask Me Anything), NAD+ expert Dr. Charles Brenner (FAQs) was asked whether Nicotinamide Riboside “NR” (FAQs) (Anecdotes) supplementation could enhance the growth of cancer. Keep in mind that Dr. Brenner takes NR daily. Here’s the Redditor’s question followed by Brenner’s response:
We’ve long known that Scripps Research’s Dr. Brunie Felding has been studying NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as a possible treatment for breast cancer. But, aside from a brief mention of her work by NAD+ expert Dr. Charles Brenner, we’ve heard virtually nothing. Until now. Chromadex (sellers of NR) recently gave consumers an opportunity to ask Dr. Felding various questions via email. The following is an email response from Dr. Felding (published with permission):
Last week, Dr. Andrew Salzman joined “The Doctor’s Farmacy with Mark Hyman M.D.” to discuss NAD+, NR (FAQs), and NMN (FAQs). Dr. Salzman made the case that if you want to raise your NAD+ levels, NMN is your best option. There are 2 problems here. First, neither Dr. Salzman nor Dr. Hyman disclosed Salzman’s ties to a company that sells NMN. Second, according to Dr. Charles Brenner (FAQs), Dr. Salzman’s case for NMN’s superiority is flawed. Brenner knows this from his own work. But, first, here’s Dr. Salzman on Dr. Hyman’s podcast:
On a podcast published this week entitled “An NAD Booster That Improves Cellular Health In The Brain“, Dr. Vilhelm Bohr, a molecular biologist, professor at the University of Copenhagen, and former chief of the Laboratory of Molecular Genetics at the National Institute on Aging (NIA), discussed his Alzheimer’s research, and his enthusiasm for NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Dr. Bohr’s research reminds us of similar work by Alzheimer’s expert Dr. Rudy Tanzi. The following is an excerpt from Dr. Bohr’s podcast interview (transcript and video below):
Back in April 2021, we heard from Kirk Carter who shared his extraordinary experience taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Testimonials). Two years later, we have an update. It gets better:
At the LD Micro Investor Conference last week, Chromadex CEO Rob Fried made the case for taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). Here’s what he said (transcript and video below):
In a 2020 podcast, Harvard’s Dr. David Sinclair explained why he took (and continues to take) NAD+ boosting supplement NMN (FAQs and Anecdotes) over fellow NAD+ booster NR (FAQs) (Anecdotes). One of his reasons was that NMN was more stable. Is this in fact true?
Last week, NAD+ expert Dr. Charles Brenner (FAQs) was a guest on the “Beauty and the BS” podcast with Dr. Peter Grossman. They covered a wide range of topics including NAD+, Nicotinamide Riboside “NR” (FAQs) (Anecdotes), NMN (FAQs, Anecdotes), and anti-aging. Most notably, Dr. Brenner said the following in response to a question about the safety of NR (video excerpt embedded below):
We’ve long known that the most successful NFL franchise of the last 2 decades takes NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). And, while we were told that the most successful major league baseball team of all time, the New York Yankees takes NR too, some were skeptical. But then there’s this from NAD+ and NR expert (and avid Boston Red Sox fan!) Dr. Charles Brenner’s (FAQs) visit to the Bronx yesterday:
In honor of Parkinson’s Awareness Month, Labiotech has a comprehensive piece examining five recent advancements in Parkinson’s disease research. Here’s an excerpt from the section on NAD+ boosting vitamin Nicotinamide Riboside “NR” (FAQs) (Anecdotes):
If you listened to former White House advisor Andy Slavitt’s recent podcast “Are We on the Verge of Curing Alzheimer’s?“, you learned a lot. But you were also surprised by the way it ended. Slavitt was joined by world renowned Alzheimer’s experts, Dr. Paul Aisen and Dr. Rudy Tanzi. Toward the end of the podcast, Dr. Aisen advised those interested in taking measures to prevent Alzheimer’s that taking supplements made no sense. You’d have expected a response from Dr. Tanzi, since we know he disagrees. But none came. So, we, at RaisingNAD reached out to Dr. Tanzi, and learned that his response to Dr. Aisen was edited out. Fortunately, the folks at Lemonada were kind enough to share Tanzi’s comments with us, which we’ve embedded and transcribed below:
You’re likely aware of the recently published and very encouraging clinical results using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) in a study relating to Alzheimer’s. If you missed it, you can catch up here and here. Late last week, the lead investigator, Dr. Christopher R. Martens gave a podcast interview to discuss results of his study. Here’s a key excerpt (podcast embedded below):
During last night’s quarterly earnings call, a fund manager asked Chromadex CEO Rob Fried about the efficacy of NMN (FAQs, Anecdotes). NMN is, of course, an NAD+ boosting supplement that competes with Chromadex’s NAD+ booster Nicotinamide Riboside (FAQs + Dosage) (Life-Changing Anecdotes). Here’s what CEO Fried said in response:
At RaisingNAD, we have limited science background. So, this site is devoted to helping other non-scientists quickly understand the complex and confusing world of NAD+ health supplements like NMN and NR. Please consider sharing this site with anyone you think might find it useful. And, if this site helps you, and you’d like to support our efforts, please contact us. We’d be grateful. The following are our most popular blog posts:
In late December, Dr. Christopher R. Martens and his team at the University of Delaware published results of a study using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). The title of their paper is “Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin“. You can read it HERE. Earlier this week, Dr. Martens was interviewed by MedicalResearch.com wherein he discussed his findings. Here are some excerpts:
Late last year, results of a human clinical study were published supporting the idea that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes), upon reaching the brain, can alter the metabolism of certain biological pathways involved in neurodegenerative diseases like Alzheimer’s. For the non-scientist, the following articles (one and two) explain the findings in plain English. For those interested in the science, see the following short video (6 minutes):
During an interview earlier this week, NAD+ expert, Dr. Charles Brenner (FAQs) was asked whether daily consumption of vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) brought cancer risk. Here’s what he said:
During a podcast interview earlier this week, Dr. Charles Brenner (FAQs) was asked about NAD+ IVs (FAQs and Anecdotes). As both an NAD+ expert, and the discoverer of Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) as an NAD+ boosting vitamin, Dr. Brenner is often asked about this increasingly popular treatment. Here’s Dr. Brenner’s most recent take:
Parkinson’s expert Dr. Charalampos (Haris) Tzoulis is actively running clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a possible treatment option for Parkinson’s patients. He’s clearly optimistic. And, as you’ll see below, this is consistent with what we’ve heard from NAD+ experts Dr. Charles Brenner (FAQs) and Dr. David Sinclair in regards to their preferred NAD+ precursors, NR and NMN, respectively:
During the Q&A portion of last week’s presentation, Parkinson’s expert Dr. Charalampos (Haris) Tzoulis was asked if, based on his ongoing clinical trials studying vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes), he had any advice for consumers looking to prevent neurological disorders such as Parkinson’s. Here’s what he said:
Dr. Charalampos (Haris) Tzoulis, a Parkinson’s expert, and Professor of Neurology and Neurodegeneration at the University of Bergen is currently overseeing clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as a possible treatment for Parkinson’s patients. In a recent presentation, Dr. Tzoulis explained why he chose to use NR as opposed to any other NAD+ precursor:
Earlier this week, Ladenburg Thalmann, a US investment firm hosted a Healthcare Symposia. One of its guest speakers was Dr. Charalampos (Haris) Tzoulis, Professor of Neurology and Neurodegeneration at the University of Bergen and Haukeland University Hospital, Bergen Norway. Dr. Tzoulis recently completed a Phase 1 clinical trial testing vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) in Parkinson’s patients. Here’s how Dr. Tzoulis explained why he initiated the study: