Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Tag: Nicotinamide adenine dinucleotide Page 6 of 8

Why are Scientists Particularly Focused on Nicotinamide Riboside (NR) and its Impact on Inflammation?

Here’s what City of Hope’s Dr. Charles Brenner (discoverer of Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin) said on a recent podcast (video embedded below):

On the Joe Rogan Podcast, David Sinclair Agrees NAD Boosters Help Fight Jet Lag

We’ve heard repeatedly that NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) helps people overcome jet lag. What about NAD booster NMN (FAQs and Anecdotes)? Well, on the Joe Rogan podcast earlier this month, Harvard’s David Sinclair said the following:

Why Does Dr. David Sinclair Take NMN Over NR?

Here’s what Harvard professor and aging researcher Dr. David Sinclair said about NMN (FAQs and Anecdotes) vs NR (FAQs) (Anecdotes) on a 2020 podcast (video embedded below):

Anecdote #21: Despite Multiple Threats, This 69-Year Old Attributes His Liver Health to Nicotinamide Riboside (NR)

On multiple occasions, we’ve heard that Nicotinamide Riboside “NR” (FAQs) (Reviews) can provide protection for the liver in conditions of metabolic stress. Our latest consumer reviewer clearly agrees. Here’s his story (please consider sharing your own NAD+ supplement experience using the form below):

A New, Cheaper, Lower Dose Nicotinamide Riboside (NR) Has Arrived. Should You Give it a Try?

Last week, Walmart introduced a new 100mg dose of Nicotinamide Riboside “NR” (FAQs) (Reviews) in partnership with Chromadex. While the FDA recommended daily dose of NR is 300mg, we’ve been told that a dose as low as 100mg can also have a therapeutic benefit. It’s reasonable to assume that since NR is expensive, this new cheaper SKU at Walmart is an effort to target a new consumer group. It also might encourage others who could afford the 300mg dose but either balk at the price or are awaiting more clinical data to finally give it a try. Here’s how Chromadex CEO Rob Fried explained the strategy in a recent interview with the TD Ameritrade Network (video embedded below):

While We Await Clinical Trial Results, Here’s Why Nicotinamide Riboside (NR) Might Help Alzheimer’s Patients

One of the main challenges for vitamin supplement companies is they can’t make health claims. It doesn’t matter how much science might back those claims — the FDA simply won’t allow supplement companies to market to specific disease states. So, how can consumers determine for themselves whether elevating NAD levels with Nicotinamide Riboside “NR” (FAQs) (Reviews) might help reduce the risk for diseases like Alzheimer’s? Well, we know that world renowned Alzheimer’s expert Dr Rudy Tanzi is launching a clinical trial with NR and believes it might work. And then there’s the following from Chromadex CEO Rob Fried on last week’s Patients Rising Podcast:

Certain Diseases that Cause Accelerated Aging are Marked by Low NAD Levels

It’s widely believed that NAD depletion is a fundamental feature of aging. This is particularly evident in certain diseases that cause accelerated aging. Chromadex CEO Rob Fried discussed this in detail on last week’s Patients Rising Podcast:

What are Pre-Clinical Studies Saying about Nicotinamide Riboside (NR) and its Impact on Cancer?

In a recent pre-clinical study, scientists at the Ho Lab looked at NAD booster Nicotinamide Riboside “NR” (FAQs) (Reviews) and its impact on cancer growth. One key conclusion: “Collectively, these findings reveal that supplementation with NR alleviates mitochondrial dysfunction and further induces additive anti-tumor immunity in conjunction with ICB (immune checkpoint blockade) treatments”. These findings are somewhat consistent with what Dr. Charles Brenner (NAD expert and discoverer of NR as an NAD precursor vitamin) has said about NR and cancer on various platforms over the last year:

Why is Nicotinamide Riboside (NR) So Expensive?

A common complaint from consumers of Nicotinamide Riboside “NR” (FAQs) (Reviews) is cost. Why is it so expensive? Here’s what Chromadex CEO Rob Fried said in response at the recent Benzinga Small-Cap Conference:

Anecdote #20: A 60-Year Old Former Pro Athlete on Why She and Her Friends Take Nicotinamide Riboside (NR)

While there’s much talk about new Chromadex paid spokesperson and Olympian Ryan Lochte and his claims that Nicotinamide Riboside “NR” (FAQs) (Reviews) helps him with recovery, repair, and energy, we at RaisingNAD are skeptical. We prefer to hear from people like Coach AJ/AJ/Angela J Nealy who receive nothing from stepping forward and sharing their experiences taking NR. And while Coach AJ isn’t an Olympic athlete, she did play in a Professional Women’s Tackle Football League! She’s also a retired Chemistry educator. The following is her story in her own words (please consider sharing your own NAD+ supplement experience using the form below):

Can We Expect a Nicotinamide Riboside (NR) Product for Pets?

Without a Nicotinamide Riboside “NR” (FAQs) (Reviews) product available for pets, some owners are taking matters into their own hands. We’ve heard from a number who’ve chosen to feed NR to their pets hoping to improve their health. Can we expect an NR product for pets? Angela Durazo (actress, former Formula 4 race car driver, former professional triathlete) was hopeful as she reached out to Dr. Charles Brenner on Twitter late last week:

VIDEO: Why the Harvard/MGH Long Hauler COVID Study Using Nicotinamide Riboside (NR) Might Have Potential

We know that many people are experiencing long haul COVID symptoms. As a result, scientists are looking for possible treatments. One of those scientists is Harvard professor and Alzheimer’s expert Dr. Rudy Tanzi who in partnership with Massachusetts General Hospital recently launched a clinical study looking at Nicotinamide Riboside “NR” (FAQs) (Reviews). Should COVID long haulers be optimistic about Dr Tanzi’s human NR study? Chromadex CEO Rob Fried weighed in on this very issue at the Benzinga Small-Cap Conference yesterday:

VIDEO: What is NAD+ Boosting B3 Vitamin Nicotinamide Riboside (NR)?

A few days ago, Chromadex Chairman Frank Jaksch spoke at the Healthspan Show. In a ~16-minute presentation entitled “Nicotinamide Riboside (NR): The Science of Aging, Cellular Health & NAD+ Precursors”, Jaksch explained NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) in plain English:

“NMN Remains Inferior to NR (Nicotinamide Riboside) Across the Board”

Here’s what Chromadex Chairman Frank Jaksch said about NAD boosting supplement NMN (FAQs and Anecdotes) vs Nicotinamide Riboside “NR” (FAQs) (Anecdotes) on yesterday’s earnings call:

Chromadex CEO on What Nicotinamide Riboside (NR) Does for Him

Here’s what Chromadex CEO Rob Fried said about vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) and how it impacts his life on yesterday’s earnings call (please consider sharing your own NAD+ supplement experience below):

Which Clinical Studies on Nicotinamide Riboside (NR) is Chromadex Most Excited About?

Here’s what Chromadex CEO Rob Fried said on a recent podcast about clinical studies looking at Nicotinamide Riboside “NR” (FAQs) (Reviews):

Anecdote #19: “I am 61 years old and my life is so much better than it’s ever been” thanks to Nicotinamide Riboside (NR)

Over the last year, we’ve heard some incredible stories from readers impacted by taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). While all of these stories are beyond extraordinary (especially Dave & Fertility, Mark & Epilepsy, Gary & Psoriasis), we’re seeing some remarkable consistency. Many people are reporting among other things: faster recovery, better sleep, improved skin, and the return of natural hair color. Today’s submission from Kirk Carter goes a step further (please consider sharing your own NAD+ supplement experience below):

VIDEO: “There are many fascinating approaches in the biotech community towards dealing with Aging…but Tru Niagen is something you can do today”

At RaisingNAD, we often highlight Chromadex CEO Rob Fried’s many podcast appearances for a very simple reason. While he never reveals any information that isn’t already publicly available, he does however often explain the merits of supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews) in new, accessible, and more persuasive ways. Last week, he joined the Insider Opportunities podcast to discuss Nicotinamide Riboside (NR):

Why Might a Healthy 20-Year Old Supplement with Nicotinamide Riboside (NR)?

While your NAD levels might not begin to decline until your mid-20s, Chromadex CEO Rob Fried has suggested that there may be times when a healthy 20-year old should consider supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews).

Anecdote #18: Nicotinamide Riboside (NR) and the Return of Natural Hair Color

Last week, we heard from Gary Varvaro who believes Nicotinamide Riboside “NR” (FAQs) (Reviews) helped cure his Psoriasis. Now comes a story from Donna about a friend suffering from Alopecia (see below). These anecdotes appear to add more credibility to the belief that NR can play a role in impacting those suffering from autoimmune diseases (please consider sharing your own NAD+ supplement experience below).

When Should You Start Worrying about NAD Decline? In a New Interview, Dr Charles Brenner Proposes a New Approach

Until now, conventional wisdom has been that your NAD levels start declining in your 20s and plunge between ages 40 and 60. But in the latest episode of Linda Cooper’s “The New 100 Longevity Campaign”, NAD expert Dr. Charles Brenner appears to have evolved his thinking. As a result, we too might have to evolve our own thinking about when to begin supplementing with NAD boosters like Nicotinamide Riboside “NR” (FAQs) (Reviews).

Anecdote #17: The NIH is Studying Nicotinamide Riboside (NR) as a Possible Treatment for Psoriasis; This Man Says It Works

Last year, the NIH launched a pilot study “to test if the dietary supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) can improve immune system function in the blood and skin of people with mild to moderate psoriasis”. According to the study’s principal investigator Dr. Michael Sack, “as the disease (psoriasis) gets more advanced, it can affect the joints, so you can get arthritis. The chronic inflammation can have systemic effects. We’re trying to see in the mild to moderate disease range whether we can prevent (these effects on the entire body)”. The NIH study is expected to be completed on September 30, 2023. In the meantime, we’re fortunate to have the following remarkable submission received yesterday (please consider sharing your own NAD+ supplement experience below):

VIDEO: A Simple Sports Analogy to Illustrate Why Raising NAD Levels Should Matter to Everyone

For most of us, NAD is a foreign concept. But, according to top scientists, it’s critical to human health. Why does NAD remain under the radar? Because it’s not a simple concept. It’s not easily accessible. So, when we at RaisingNAD find an interview or video which explains NAD in plain simple English we jump at the opportunity to share it. The following is an example from last week:

The 2-Minute Case for Nicotinamide Riboside (NR) vs NMN

There’s endless discussion online about which NAD boosting vitamin supplement to take — Nicotinamide Riboside “NR” (FAQs) (Anecdotes) or NMN (FAQs and Anecdotes). As a result, potential customers are often left confused without any idea which to choose. The following transcript may provide some clarity.

Top Alzheimer’s Expert Formally Announces Much Anticipated Long-Haul COVID Study Using Supplement Nicotinamide Riboside (NR). Why is This Important?

In numerous recent interviews (Here and Here), top Harvard Alzheimer’s expert Dr Rudy Tanzi discussed plans to initiate 2 human clinical studies using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). In one study, Dr Tanzi will focus on Alzheimer’s patients. And in the other, which was posted on ClinicalTrials.gov earlier this week Dr Tanzi will focus on long-haul COVID patients experiencing persistent cognitive and physical symptoms. You may remember that Dr Tanzi knows a lot about NR through both personal supplementation (“I religiously take Tru Niagen“) AND his association with the NFL’s New England Patriots. As a result, many have been eagerly awaiting these two clinical trials. Here’s more on the COVID trial posted earlier this week:

“As Long As You Have Access To Nicotinamide Riboside (NR), There Is Really No Purpose For Using NMN”

While NAD boosting supplement NMN (FAQs and Anecdotes) remains incredibly popular especially in China, the folks at Chromadex continue to make the case that Nicotinamide Riboside “NR” (FAQs) (Anecdotes) is your better option. Chairman Frank Jaksch made the case in early March. And last week, Dr Andrew Shao weighed in as well in an interview with NUTRA Ingredients Asia. See HERE.

A Look at the All-Star Team of Scientists Studying the Potential of Nicotinamide Riboside (NR)

We know that there’s enormous interest in studying Nicotinamide Riboside “NR” (FAQs) (Reviews) in the science community. A quick look at the 50+ ongoing or completed clinical trials says it all. But who are these scientists? Chromadex CEO Rob Fried talked about some of them at the Oppenheimer Health Care Conference yesterday.

What Should You Expect to Feel from Taking Nicotinamide Riboside (NR)?

What should you expect to feel from supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews)? Do consumers tend to increase their dose over time? Here’s what Chromadex CEO Rob Fried said at the Oppenheimer Health Care Conference yesterday:

Popular YouTube Health Channel Puts Nicotinamide Riboside (NR) at the Top of List of Brain Supplements

A popular YouTube channel called Bestie (3.4m subs) posted a short but substantive video this week with Nicotinamide Riboside “NR” (FAQs) (Reviews) topping a list of “6 Supplements That’ll Help You Build A Better Brain” (Turmeric, Lion’s Mane Mushrooms, Seafood, Vitamin D3). Transcript and video embedded below.

Anecdote #16: Pet Cat Walking Better and Back to Eating Kibble. Owner Attributes This to B3 Vitamin Nicotinamide Riboside (NR)

While we’ve heard from many consumers reporting life-changing experiences thanks to supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews), we’re now hearing more and more from pet owners too. This latest story was submitted yesterday (please consider sharing your own NAD+ supplement experience below).

Who Takes Nicotinamide Riboside (NR)?

As a public company, Chromadex has few opportunities each year to talk openly with the public about Nicotinamide Riboside “NR” (FAQs) (Reviews). Last evening was one of those times. The following are key quotes from Chromadex CEO Rob Fried and Chairman Frank Jaksch during management’s Q4 2020 earnings call.

Analysts Assess Recent Developments with Nicotinamide Riboside (NR)

In advance of this week’s earnings call, Wall Street analysts at B Riley published a note today on Chromadex and recent developments relating to Nicotinamide Riboside “NR” (FAQs) (Reviews). The following are key excerpts.

NMN vs. NR – What Should You Do?

We’ve covered this often asked and endlessly debated question repeatedly at RaisingNAD. Scientists say Nicotinamide Riboside (NR) is the better choice — and Nestlé Health Science (a subsidiary of Nestlé), which recently launched a new product with NR as the key ingredient, calls NR: “the most efficient NAD+ precursor“. Yet, NMN (FAQs and Anecdotes) remains incredibly popular. So what should you do? Well, while Chromadex Chairman Frank Jaksch is obviously in the NR camp, he recently made a compelling case in plain English why the choice should be obvious.

Chromadex Chairman: “Mounting Evidence Has Linked Compromised NAD+ Status to the Hallmarks of Aging”

In a rare appearance, Chromadex Founder and current Executive Chairman Frank Jaksch joined the “Cellular Health: The Next Big Market Opportunity“ webcast last week to discuss NAD, Nicotinamide Riboside “NR” (FAQs) (Anecdotes), NMN (FAQs and Anecdotes), aging and more. According to his bio, Jaksch is not your ordinary Executive Chairman. He currently oversees research, strategy, and operations for ChromaDex, with a focus on scientific and novel products for the pharmaceutical and nutraceutical markets. During this webcast, Jaksch had a lot of substantive things to say. As a result, we’re posting a transcript of his entire ~10-minute presentation.

Unique Opportunity to Participate in Chromadex’s (CDXC) Upcoming Earnings Call

Never before have retail investors been more important to the prospects of small-cap public companies both to drive their businesses and their share prices through the use of social platforms. Let’s leave aside the recent exceptional case of GameStop (GME). But look what retail did to possibly save AMC (ticker: AMC). Incredible. As for small-caps like Chromadex (CDXC) (Nicotinamide Riboside or NR), its management undoubtedly realizes that their vocal community of early adopters (many of whom are also retail shareholders) have played a significant role in driving sales through “Word of Mouth” by sharing their experiences online and encouraging others to give NR a try. Rarely do you see such an active community take daily to Facebook, Reddit, Twitter and even Seeking Alpha (Disclosure) to spread word of the merits of a consumer product. This community represents a remarkable asset. As a result, Chromadex management has agreed to consider community questions for their upcoming March 10th earnings call. While management is obviously limited in what they can say, let’s use this opportunity to tell them what’s on our minds in the comments section below. And, of course, we’ll also enjoy the added benefit of hearing what’s on the minds of other smart investors, scientists, and consumers who are as interested as we are in the future of Nicotinamide Riboside “NR” (FAQs) (Reviews).

Positive Phase 3 COVID Study Results Released; Remember Dr Brenner’s Response to Phase 2

Last week, a new Phase 3 human clinical study conducted in Turkey demonstrated that patients with mild-to-moderate COVID-19 who received the standard of care experienced a 3.5 day reduction in recovery time when receiving a nutritional protocol. The nutritional protocol included Nicotinamide Riboside “NR” (FAQs) (Reviews). These Phase 3 results follow Phase 2 data which were published in October 2020. Below are Dr Charles Brenner’s (who discovered NR as an NAD precursor vitamin) evaluation of the two studies and his opinion on the role of NR.

Nestlé Health: “There’s NMN, but then there’s NR (Nicotinamide Riboside) which is the most efficient NAD+ precursor”

During a webcast yesterday titled “Cellular Health: The Next Big Market Opportunity“, Nestlé Health Science’s Joelle Legree spoke at great length explaining the strategy behind the recent launch of Celltrient. Of course, Celltrient is Nestlé Health’s (a Nestlé subsidiary) new brand focused on cellular health. And, for those interested in raising NAD levels, one of Celltrient’s three new products “Celltrient Energy” contains Nicotinamide Riboside “NR” (FAQs) (Reviews). How does Nestlé Health and its team of scientists feel about the NR vs NMN debate? Key quotes:

Nestlé Health Explains N.A.D. and Makes the Case for Nicotinamide Riboside (NR)

As we’ve discussed previously, Nestlé Health (a subsidiary of Nestlé) recently introduced a new product containing Nicotinamide Riboside “NR” (FAQs) (Reviews) in partnership with Chromadex. Since then, Nestlé has launched a vigorous campaign to educate the general public about N.A.D. and NR in an effort to accelerate consumer adoption of its various new Celltrient products. At RaisingNAD, we’re always on the lookout for content that explains NAD and NR in plain, non-scientific English — even if it comes from an advertisement. So, here’s some key quotes from a Nestlé “Sponsored Article” in Newsweek:

10 Most Popular Posts

As the share price of Chromadex increased dramatically this week, many investors learned about Nicotinamide Riboside “NR” (FAQs) (Reviews) for the first time. The following are RaisingNAD’s most popular blog posts of the last year:

Should You Take Breaks from Vitamin Supplement Nicotinamide Riboside (NR)?

In response to a Twitter question this weekend from Bill Walker about whether it’s beneficial to take breaks from vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), Dr. Charles Brenner (who discovered NR as an NAD precursor vitamin) said the following.

Should Those Suffering from Parkinson’s Disease Supplement with Nicotinamide Riboside (NR)?

We know that one of the world’s top Alzheimer’s experts recently initiated clinical trials testing vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) on human patients. But what about Parkinson’s disease? Both Dr David Sinclair and Dr Charles Brenner agree that there’s good reason for clinical trials testing NAD boosters on those suffering from neurodegenerative diseases. So, what’s the latest? Dr. Brenner (NAD expert and discoverer of NR as an NAD precursor vitamin) made the following comment on Twitter earlier this week.

PODCAST: Family Physician on Her Experience Taking Nestle’s New Nicotinamide Riboside (NR) Product

Last week, Dr. Noelle Reid, a family physician and founder of Trinity Health and Wellness Medical Group joined the NutraCast Podcast (embedded below) to build awareness for Nestlé Health’s new initiative “Age-Associated Cellular Declin‪e‬” and its related Celltrient brand. While Dr Reid is compensated for her role as a consulting physician for Nestlé’s Celltrient, she clearly understands and appreciates the importance of Nicotinamide Riboside “NR” (FAQs) (Reviews). The following are key podcast quotes.

At 43, the NFL’s Tom Brady Appears to Defy Aging. Nicotinamide Riboside (NR) May Have Something To Do With It

At the age of 43, Tampa Bay Buccaneers quarterback Tom Brady won his 7th Super Bowl last night. How does he continue to excel at such a high level into his 40s when most NFL athletes have long retired? The New York Times says it’s “Through Genetics, Luck or ‘Prehab“. But NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) may also be playing a role. See HERE.

Cornell Vet Prof on Vitamin Supplement Nicotinamide Riboside (NR) for Pets: “theoretically NR should be very safe and very likely has benefit”

Last week, Cornell University hosted a webinar entitled Bone Appétit: Is Your Pet’s Nutrition the Key to Health, Wellness, and Longevity? (video embedded below). Since we’ve heard numerous anecdotes from people who’ve fed supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) to their pets, I was curious if the panel (which included the Chief Veterinary Officer at Nestle Purina) had done any work in this area. It seemed plausible considering that another Nestle division Nestle Health recently launched a new brand with NR as a key ingredient.

NAD Explained in 5 Tweets

While not yet well known or understood by the general public, the NAD system is crucial to all of our lives. NAD expert Dr. Charles Brenner (who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD boosting vitamin supplement) explained NAD in a handful of Tweets earlier today:

Why Are There So Many Clinical Trials to Test Nicotinamide Riboside (NR) in People?

If you’re focused on maintaining your NAD levels, you should be aware that simply eating a healthy diet may not be enough. And since your NAD system can also be disturbed by inflammation, aging, and conditions of metabolic stress, there’s a case to be made for supplementation with Nicotinamide Riboside “NR” (FAQs) (Reviews). Dr. Charles Brenner (who discovered NR as an NAD precursor vitamin) made that case in a recent Twitter thread and also explained the abundance of ongoing clinical trials testing NR:

“NMN Converts to NR (Nicotinamide Riboside) before entering cells”

Much to the disappointment of Dr. Charles Brenner, the supplement NMN (FAQs and Anecdotes) remains incredibly popular. Dr Brenner, who discovered Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as an NAD precursor vitamin has repeatedly made the case against NMN arguing that it “makes no sense“. In response to some Twitter questions this week, Dr Brenner said the following:

“Virtually every disease that we associate with aging is also associated with reduced NAD levels”

Chromadex CEO Rob Fried joined Late Night Health Radio this week to discuss NAD and NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). The following are key quotes:

Do You Need to Refrigerate Nicotinamide Riboside (NR)?

In response to a Twitter question, Dr. Charles Brenner who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin said the following about NR and whether you need to refrigerate:

Anecdote #15: “the feeling that I’m just kind of impervious to colds is the single most astonishing thing”

We’ve heard some incredible stories here from consumers impacted by supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews). Who can forget Mark’s story about his successful battle with epilepsy? What about Shelly overcoming Restless Leg Syndrome (RLS)? The anecdotal evidence appears endless. Now comes a remarkable submission from Igor V (please consider sharing your own NAD+ supplement experience below):

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