There’s endless discussion online about which NAD boosting vitamin supplement to take — Nicotinamide Riboside “NR” (FAQs) (Anecdotes) or NMN (FAQs and Anecdotes). As a result, potential customers are often left confused without any idea which to choose. The following transcript may provide some clarity.

Chromadex CEO Rob Fried at last week’s LD Micro Conference:

“…there are other companies out there who have molecules that are claiming to elevate NAD.

One that is gaining popularity is called NMN, Nicotinamide Mononucleotide.

NMN is a precursor to NAD.

However, all NMN essentially is is Nicotinamide Riboside (NR) with a phosphate attached to the perimeter.

So it’s expensive to make NMN because you have to start by making Nicotinamide Riboside (NR).

Then you add the phosphate.

Then you take NMN — and the phosphate blocks entrance into the cell.

There’s no transport mechanism in the cell.

So in the bloodstream that phosphate is removed.

It turns back into NR in the bloodstream — and then enters the cell.

So it absolutely makes no sense to take NMN.

All it really is is extremely expensive, inefficient Nicotinamide Riboside (NR).

But because we have patents and controls over Nicotinamide Riboside (NR) swarms of competitors are coming into the market touting NMN.

It’s a significantly inferior product that doesn’t have regulatory approvals or patents or the same amount of research studies.

BUT we do believe NMN elevates NAD — just not nearly as well as NR and not as efficiently as NR.

And frankly Chromadex has some patents around NMN.

But we know it’s an inferior product.

So we don’t sell it.”

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