We know there’s significant interest in NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a potential treatment for Alzheimer’s Disease (Link). It appears the same can now be said for NR and Parkinson’s. The following are results of a Phase 1 clinical trial published yesterday (Note: A Phase 2 study is already underway):
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As a result of this paper, many believe there’s a transporter that carries NAD+ booster NMN (FAQs and Anecdotes) into cells. Dr. Charles Brenner, who discovered Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as an NAD+ booster vitamin says the notion of the existence of a transporter is mistaken. Below, he makes the case:
What can be done to help COVID-19 long haulers? Well, some scientists believe that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) could be a treatment solution. One of those scientists is Harvard Alzheimer’s expert Dr. Rudy Tanzi. And he recently initiated a human clinical trial to see if he’s correct (UPDATE: Results expected soon). Here are some key quotes regarding the clinical trial:
There’s reason to believe that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) could be helpful to those suffering from neuropathy. Dr. Charles Brenner (FAQs), who discovered NR as an NAD+ boosting vitamin certainly believes so. Below are quotes from Dr. Brenner on the NAD+ science, current clinical trials, and consumer anecdotes:
During an interview last week, City of Hope’s Dr. Charles Brenner (FAQs) was asked about his daily supplement regimen. Of course, one would assume his regimen includes NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Here’s what he said:
In a lengthy WebMD piece published earlier today, Lisa Marshall details her father’s depressing decline at the hands of Alzheimer’s disease. Despite her father’s death, Marshall explains there’s reason for hope. Scientists are exploring possible ways of fighting back against Alzheimer’s including the use of NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Key excerpts from the WebMD piece:
Harvard’s Dr. Rudy Tanzi is a leading expert studying Alzheimer’s disease. He also happens to be a passionate believer in NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). As a result of his lab work, he’s launching a clinical trial looking at NR in individuals with mild cognitive impairment (MCI) and mild Alzheimer’s dementia (AD) (actual start date March 2, 2022). Here’s why:
Without the existence of a commercial product specific to pets, many people are turning to NAD+ boosting B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) to help improve the health of their cats and dogs. Here’s what scientists and pet owners are saying about their experiences with NR:
As people learn more about the importance of elevating NAD+ levels to improve health by taking supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes), NMN (FAQs and Anecdotes), or getting NAD+ IV drips (FAQs), many questions inevitably follow. Here are links to blog posts answering many of your pressing questions:
On a recent podcast, Harvard’s Dr. David Sinclair was asked about concerns that NAD boosting supplement NMN (FAQs & Anecdotes) causes cancer growth. Here’s what he said:
The anecdotal evidence continues to grow that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) might be helpful to those struggling with fertility. We’ve already heard from a Harvard-trained fertility expert who recommends NR to patients. We’ve also heard from Dave Crouse (“Our Niagen Baby”) who believes NR was his family’s game-changer. Now comes Reddit member MuseAndMuse20 who started taking NR in August 2021 and just this past week shared a remarkable story that should give everyone struggling to have children some motivation to continue to pursue their dream:
Are there are any known side effects associated with taking B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), in this case NR brand niagen? This is one of the most common questions we hear from potential consumers relating to NR. In the past, we’ve heard there aren’t any adverse effects. And in an interview last week, we heard this:
We know that world renowned Alzheimer’s expert Dr. Rudy Tanzi believes in B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). He takes NR daily, he’s conducting a clinical trial studying NR as a possible treatment for Alzheimer’s, and he also recently recommended it to Dr. Oz’s mother who’s currently suffering from that very debilitating disease. What about NR as a possible treatment for Parkinson’s? There’s reason to believe NR could help. Here’s the latest on a recent Parkinson’s/NR clinical trial out of Norway:
Many companies have come forward over the last 2 years claiming they have treatments for COVID. And most of those claims have turned out to be nonsense. On the flip side, some companies have products that have been shown in human studies to be effective against COVID, and yet they’re prevented from informing the general public by restrictions imposed by regulatory bodies. One of those products appears to be NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews):
It should come as no surprise to readers of this site that the wildly successful New England Patriots take a daily dose of B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). We presented overwhelming evidence of this back in August 2020. Of course, it remained unacknowledged until this past week:
Over the last year, we’ve heard from various people who believe their pets are benefiting from taking NAD boosting human vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). You can read their anecdotes here: (Cat) (Cat) (Dog). But is there an actual NAD booster for dogs on the way? Harvard’s Dr. David Sinclair explained on a recent podcast:
We’ve heard from many consumers telling us remarkable stories of hair benefits thanks to supplementing with B3 vitamin Nicotinamide Riboside “NR” (FAQs) (Reviews). In particular, they report changes to their hair color, hair thickness, and speed of hair growth. Here are some examples (please consider sharing your own NAD+ supplement experience using the submission form below):
We’ve heard from many consumers telling us remarkable stories of their experiences taking B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). While their anecdotes about skin transformation are remarkable, they’re not particularly surprising considering there’s already an NR skin care product on the market. That said, these consumer anecdotes are life-changing:
In a segment this week entitled “What Regimen Does Dr. Oz Have His Mother On In Her Battle Against Alzheimer’s?”, Dr. Oz talked to Dr. Rudy Tanzi, Alzheimer’s expert and Professor of Neurology at Harvard. Dr. Tanzi offered a series of recommendations including taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews).
We continue to hear from people who believe their pets are benefiting from taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). You can read those anecdotes HERE. The latest comes this week from dog owner Ben (please consider sharing your own NAD+ supplement experience using the form below):
We’ve previously heard from a Harvard trained fertility specialist who recommends NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) to patients looking to improve egg quality. We’ve also heard anecdotal evidence from people struggling with fertility that NR might be a treatment solution (“Our Niagen Baby“). Now comes Harvard’s Dr. David Sinclair on a podcast earlier this week claiming he too believes that NAD boosting supplements (in this case, NMN (FAQs and Anecdotes)) may help aspiring parents (video embedded below):
If you’re considering doing NAD IV drip therapy rather than simply taking oral NAD+ boosting supplements like Nicotinamide Mononucleotide “NMN” (FAQs) or Nicotinamide Riboside “NR” (FAQs) (Reviews) you’ve come to the right place. The following might help you make a decision (UPDATE: a more effective, less painful, quicker, cheaper option may have just arrived — “NR” IV):
Joe Rogan has said he learned about NAD IV drips (FAQs) from podcaster Ben Greenfield. And Ben Greenfield has said he was sold on NAD IV drips after talking to someone in the NAD IV business (see below). Where does the science stand on NAD IVs? Well, in 2018, Ben Greenfield hosted NAD expert Dr Charles Brenner to hear his perspective (Note: Brenner’s opinions clearly haven’t changed):
Despite skepticism from some NAD experts, NAD IV drip therapy (FAQs) appears to be gaining momentum thanks in large part to podcaster Joe Rogan. But, back in late 2018, FoundMyFitness‘ Dr. Rhonda Patrick said the following on the aforementioned Joe Rogan Experience (we have no evidence that her opinion has changed):
Earlier this week, we explored whether taking a daily Resveratrol along with supplements Nicotinamide Riboside “NR” (FAQs) (Reviews) or NMN (FAQs) affords any health or longevity benefits. A former labmate of Dr David Sinclair says the answer is likely “no”. Now comes Dr Charles Brenner (NR and NAD expert) who agrees that “Resveratrol is hype”. He made the case on a recent podcast:
There are often discussions online about taking a daily Resveratrol along with either Nicotinamide Riboside “NR” (FAQs) (Reviews) or NMN (FAQs). But should you follow this regimen? While Harvard’s Dr David Sinclair does (Resveratrol + NMN), his former labmate at MIT, Dr Matt Kaeberlein (who’s now a prominent scientist studying aging at the University of Washington) does not. He calls Resveratrol‘s impact on health and longevity likely a myth that unfortunately continues to dupe the public.
Below is an excerpt from a conversation between Harvard’s Dr. David Sinclair and Stanford neuroscientist Andrew Huberman where Sinclair is asked what NMN (FAQs and Anecdotes) brand he recommends:
Readers of this site have been kind enough to submit a remarkable number of reviews of their experiences taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs). Below is a simple list to help you quickly find what you’re looking for. Please consider sharing your own NAD+ supplement experience by filling out the form below. You’ll undoubtedly help others by doing so.
A graduate of the Albert Einstein College of Medicine, Ronald Hoffman MD hosts The Intelligent Medicine Podcast (300 episodes). He often talks about taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) and why he recommends it to his patients. During last week’s podcast with co-host Leyla Muedin, MS, RD, CDN, Dr Hoffman responded to a question about the potential for NR to promote cancer tumor growth:
In September, scientists reported promising results from a clinical study treating patients suffering from Ataxia Telangiectasia (AT) with NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). For those unfamiliar, according to the Cleveland Clinic, “Ataxia is the term for a group of neurological diseases (diseases related to the nervous system) that affect movement and coordination”. Last week, the folks at NR seller Chromadex discussed the clinical findings during their latest earnings call:
We’ve heard a number of anecdotes from consumers claiming that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) helped reduce or eliminate their arthritis. One example is Coach AJ (Anecdote #20). And, of course, this is no surprise to some with knowledge of metabolism and aging that raising NAD levels can be helpful in the fight against arthritis. For those looking for more evidence of the NAD-NR-arthritis connection, the following is a personal story in a short but substantive video from “Stay on the Health Track” (YouTube 2.7k subs):
As part of her daily health and wellness regimen, reality star and entrepreneur Kourtney Kardashian just announced she takes NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Of note, there’s no evidence she’s being compensated for making the following glowing public endorsement. Here’s what she said yesterday on her site and on Twitter (please consider sharing your own NAD+ supplement experience below):
As we know, NAD (Nicotinamide Adenine Dinucleotide) is essential to the normal functioning of every cell in our body. But NAD gets depleted over time due to the many instances of body stress we experience in our lives. One of those instances of body stress can occur when we play sports. And when our NAD levels are disturbed or reduced due to any kind of sports related contact or injury, we’re likely experiencing what’s called “metabolic stress”. As a refresher, metabolism is the chemical reactions in the body’s cells that changes food into energy. Our bodies need this energy to do everything from moving to thinking to growing. So, why are so many athletes including (though not acknowledged) the NFL’s New England Patriots taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews)?
Most of us hate needles. But if that were the only way to raise our NAD levels, many of us might embrace NAD IV drips (FAQs). Fortunately, NAD expert Dr. Charles Brenner, who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD boosting vitamin says you don’t need to choose the needle option. He explained further on a recent episode of Dr Will Cole’s podcast “The Art of Being Well“:
Last week, Mark Molinaro, who previously reported being seizure-free thanks to vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) returned to us with more to share. He showed us his recent liver and kidney blood test results which demonstrated remarkable improvement. He attributes that improvement to an increase in his daily dose of NR. This reminded us of a Twitter question in 2020 where Dr, Charles Brenner (who discovered NR as an NAD boosting vitamin) was asked whether there’s a lab test to objectively measure the impact of taking NR. Here’s what he said:
You may be quick to dismiss Mark Molinaro and his claim that Nicotinamide Riboside “NR” (FAQs) (Reviews) put an end to his devastating epileptic seizures. He doesn’t expect you to believe him either. But now he’s back with an anecdote about his dramatically improved liver and kidney blood test results which he attributes to an increase in his daily dose of NR (please consider sharing your own NAD+ supplement experience below):
Many people are searching for vitamin supplements to help improve their egg quality. We recently learned of a Harvard trained fertility expert who recommends Nicotinamide Riboside “NR” (FAQs) (Reviews). We’ve since learned of another fertility specialist who’s equally enthusiastic about NR and recommends it to his patients. Below is a short 5-minute video where he explains why:
After contracting COVID, outspoken podcaster Joe Rogan fought back with a treatment plan that included NAD IV drips (FAQs). For some (but not all), NAD drips are a preferred alternative to NAD boosting supplements Nicotinamide Riboside “NR” (FAQs) (Reviews) and NMN (FAQs). Below is Rogan’s Instagram video where he provides more detail:
Last week, we wrote a blog post about the supplement NMN (FAQs and Anecdotes) entitled “If NMN is Safe, Why Don’t Regulators Approve It?“. We were subsequently made aware of an article by a group of scientists published last month in the Journal of Advanced Research entitled “Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns“. It raises serious concerns about the safety of NMN. The following are the authors’ conclusions:
Much to my surprise, lots of people take NAD+ boosting supplement NMN (FAQs and Anecdotes). But as readers of this site know, I’m certainly not one of them. While I’m sold on the importance of boosting NAD+ levels, I defer to the regulatory authorities in charge of evaluating consumer safety to determine which NAD booster to take. And hands down, it’s Nicotinamide Riboside “NR” (FAQs) (Anecdotes). It’s not even close. NR has been deemed safe by the FDA (NDI), Health Canada, EFSA, Australian TGA, and achieved GRAS status — NMN has received none of these approvals. What about the general science community? Well, they’ve clearly made their choice, too. There are currently 67 human clinical trials at some stage testing NR as a treatment for various diseases — only 14 trials for NMN. This suggests that scientists overwhelming choose NR when testing NAD boosters on human subjects. As well, the scientists at Nestlé chose NR over NMN when launching new food and beverage products selling to the general population. But while NR appears the safe choice, it remains abundantly concerning that even with the lack of regulatory body safety recognition, there’s obviously so much consumer demand for NMN that there are MANY companies still selling it. And each of these companies is selling something different. So it’s virtually impossible to know what you’re actually ingesting when taking NMN. And yet NMN remains incredibly popular. It’s a marketing triumph of significant proportions that so many consumers have been convinced to put something in their bodies that has so many red flags in plain sight. And then comes this:
On numerous occasions, Dr. Charles Brenner (who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin) has responded to questions about taking NR under the tongue: