You’re likely aware of the recently published and very encouraging clinical results using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) in a study relating to Alzheimer’s. If you missed it, you can catch up here and here. Late last week, the lead investigator, Dr. Christopher R. Martens gave a podcast interview to discuss results of his study. Here’s a key excerpt (podcast embedded below):
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During last night’s quarterly earnings call, a fund manager asked Chromadex CEO Rob Fried about the efficacy of NMN (FAQs, Anecdotes). NMN is, of course, an NAD+ boosting supplement that competes with Chromadex’s NAD+ booster Nicotinamide Riboside (FAQs + Dosage) (Life-Changing Anecdotes). Here’s what CEO Fried said in response:
At RaisingNAD, we have limited science background. So, this site is devoted to helping other non-scientists quickly understand the complex and confusing world of NAD+ health supplements like NMN and NR. Please consider sharing this site with anyone you think might find it useful. And, if this site helps you, and you’d like to support our efforts, please contact us. We’d be grateful. The following are our most popular blog posts:
In late December, Dr. Christopher R. Martens and his team at the University of Delaware published results of a study using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). The title of their paper is “Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin“. You can read it HERE. Earlier this week, Dr. Martens was interviewed by MedicalResearch.com wherein he discussed his findings. Here are some excerpts:
Late last year, results of a human clinical study were published supporting the idea that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes), upon reaching the brain, can alter the metabolism of certain biological pathways involved in neurodegenerative diseases like Alzheimer’s. For the non-scientist, the following articles (one and two) explain the findings in plain English. For those interested in the science, see the following short video (6 minutes):
During an interview earlier this week, NAD+ expert, Dr. Charles Brenner (FAQs) was asked whether daily consumption of vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) brought cancer risk. Here’s what he said:
During a podcast interview earlier this week, Dr. Charles Brenner (FAQs) was asked about NAD+ IVs (FAQs and Anecdotes). As both an NAD+ expert, and the discoverer of Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) as an NAD+ boosting vitamin, Dr. Brenner is often asked about this increasingly popular treatment. Here’s Dr. Brenner’s most recent take:
Parkinson’s expert Dr. Charalampos (Haris) Tzoulis is actively running clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a possible treatment option for Parkinson’s patients. He’s clearly optimistic. And, as you’ll see below, this is consistent with what we’ve heard from NAD+ experts Dr. Charles Brenner (FAQs) and Dr. David Sinclair in regards to their preferred NAD+ precursors, NR and NMN, respectively:
During the Q&A portion of last week’s presentation, Parkinson’s expert Dr. Charalampos (Haris) Tzoulis was asked if, based on his ongoing clinical trials studying vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes), he had any advice for consumers looking to prevent neurological disorders such as Parkinson’s. Here’s what he said:
Dr. Charalampos (Haris) Tzoulis, a Parkinson’s expert, and Professor of Neurology and Neurodegeneration at the University of Bergen is currently overseeing clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as a possible treatment for Parkinson’s patients. In a recent presentation, Dr. Tzoulis explained why he chose to use NR as opposed to any other NAD+ precursor:
Earlier this week, Ladenburg Thalmann, a US investment firm hosted a Healthcare Symposia. One of its guest speakers was Dr. Charalampos (Haris) Tzoulis, Professor of Neurology and Neurodegeneration at the University of Bergen and Haukeland University Hospital, Bergen Norway. Dr. Tzoulis recently completed a Phase 1 clinical trial testing vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) in Parkinson’s patients. Here’s how Dr. Tzoulis explained why he initiated the study:
Earlier today, Dr. Charles Brenner (FAQs) was asked whether NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) might help those suffering from Myocarditis (which occurs when the heart muscle becomes inflamed). Here’s his response:
Last week, results of a clinical study were released bringing new hope for Alzheimer’s patients: “Our results indicate that treatment of AD patients with CMA (full list) can lead to enhanced cognitive functions and improved clinical parameters associated with phenomics, metabolomics, proteomics and imaging analysis.” While this is clearly encouraging news, we’re quick to defer to the expertise of those better positioned to analyze the study results to tell us what they mean. And there’s no one better than Alzheimer’s expert Dr. Rudy Tanzi — who also happens to be a passionate consumer of one of the CMAs in the latest study, Nicotinamide Riboside “NR” (FAQs) (Reviews).
You’ve probably read about 45-year-old Bryan Johnson (Bloomberg: How to Be 18 Years Old Again for Only $2 Million a Year). He sold a company to eBay and is now taking extreme measures to try to be physically and mentally 18 again. Among the 24 supplements he takes each day is NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes):
We recently heard from an excellent new site, “Science of NAD”, that “numerous mouse studies show that NAD replenishment can protect oocytes“. And here at RaisingNAD, we’ve compiled compelling evidence from experts and consumers that NAD+ boosters, Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) might possibly help those struggling with fertility by improving egg quality. See HERE. So, where does that leave us? When will we know whether the results of these mouse studies are a viable, evidence-based treatment option for humans? Fortunately, earlier this week, NAD+ expert Dr. Charles Brenner (FAQs) was asked about this very issue on Twitter:
If the Kardashians are interested, one can assume they smell opportunity. That appears to be the case with NAD+. Last year, Kourtney K. touted NR. She now appears to have soured on NR, and is currently embracing NMN. Separately, her sister Kendall loves NAD+ IVs. Are these science based decisions?
There’s a growing belief that NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes) might play a role in improving fertility chances. We’ve compiled the opinions of fertility specialists, NAD+ experts, as well as a number of real-life consumer anecdotes HERE. To bolster the case, “Science of NAD” recently published an exhaustive look at the scientific evidence supporting the connection between higher NAD+ levels and fertility. Here’s their conclusion:
We’ve long known what Dr. David Sinclair says he feels from taking NAD+ booster NMN (FAQs and Anecdotes). Now we know what Dr. Charles Brenner (FAQs) believes he experiences from taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes). From last week’s “Making Sense of Science” podcast:
There’s been a lot of confusion lately regarding the possible connection between NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) and cancer. You can read more HERE. Fortunately, this past week, Matt Fuchs, editor-in-chief of Leaps.org asked NAD+ expert Dr. Charles Brenner (FAQs) about the issue during the “Making Sense of Science” podcast. Key quotes and podcast embedded below:
Dr. Charles Brenner (FAQs) is often asked when is the right time to start taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). His answer to this question in a Twitter exchange yesterday likely explains why some professional sports teams including the New England Patriots, Kansas City Chiefs, Tampa Bay Buccaneers, and New York Yankees are reportedly frequent consumers:
Once you decide to take an NAD+ boosting supplement, the next big challenge is deciding which one. The following is a list of people who take Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). Perhaps this list will help you. We’ll continue to update it regularly:
While we typically avoid sharing articles about people who are compensated for recommending NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes), we’re doing so here to highlight how Jessica Alba’s trainer explains NAD+ and the case for supplementation. From “The Chalk Board (A Guide to Living Well)“:
An article this past weekend in the Toronto Sun claims that “Brain fog”, a typical symptom of long COVID, is currently a major concern for both scientists and sufferers alike. One possible treatment being tested is NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). Key quote:
Those who question the efficacy of NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) often point to the work of Princeton’s Dr. Joshua Rabinowitz. Here’s a clip of Dr. Rabinowitz in an appearance on Dr. Peter Attia’s podcast explaining his reasoning followed by a response from NAD+ and NR expert Dr. Charles Brenner:
While we await more conclusive evidence from clinical trials studying NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), we have the luxury of consumers sharing their own personal experiences here at RaisingNAD. You can see the full alphabetical list of diseases and conditions impacted here. The latest consumer submitted anecdote comes from Phil L. who resides in Honolulu, Hawaii (please consider sharing your own experience below):
During his Intelligent Medicine Podcast earlier today, Dr. Ronald Hoffman MD addressed “a flurry of listener questions” about Nicotinamide Riboside “NR” (FAQs) (Reviews) and cancer. These questions were in response to this week’s news article entitled “Popular Dietary Supplement Causes Cancer Risk and Brain Metastasis” which we covered here. Here are key quotes from Dr. Hoffman (podcast embedded below):
During the latest “Reason with Science” podcast, NAD+ expert Dr. Charles Brenner (FAQs) discussed the many sources of NAD+ in our food supply. Here’s what he said about beer and NAD+ boosting vitamin Nicotinamide Riboside “NR” (FAQs) (Reviews):
As the popularity of NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) grows, so do the number of consumer questions. To answer many of these questions, we have the luxury of turning to Dr. Charles Brenner who discovered NR as an NAD+ boosting vitamin and who often shares his scientific, evidence-based opinions on various podcasts:
According to an article about new research from the University of Missouri (research behind paywall), NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Consumer Anecdotes) could increase the risk of developing breast cancer that metastasizes to the brain. But before drawing your own conclusions, you might consider the following responses from the leading authority on NR (Dr. Charles Brenner) as well as one of the authors of the study (Carles Canto):
Last week, a Twitter user asked Dr. Charles Brenner for research on the potential neuroprotective benefits of NAD+ vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Consumer Anecdotes). Here’s how Dr. Brenner responded:
In a November 4th article entitled “Does Taking an NAD Supplement Really Have Anti-Aging Effects?“, Shape Magazine offered an accessible look at the NAD+ space including supplements Nicotinamide Riboside “NR” (FAQs) (Consumer Anecdotes) and NMN (FAQs & Anecdotes). Here’s what they said about the complicated process of choosing an NAD+ supplement:
During a recent interview at the Longevity Investors Conference, Dr. Charles Brenner was asked whether NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Consumer Anecdotes) should be considered a longevity intervention. Here’s what he said (video and transcript below):
While we await results of clinical trials, we continue to hear remarkable consumer anecdotes claiming significant improvements thanks to NAD+ boosting supplements Nicotinamide Riboside “NR” (FAQs) (Reviews) and NMN (FAQs). The latest anecdote comes from Ron Smith (please consider sharing your own NAD+ supplement experience using the form below):
Many have heard of NAD+ — but few understand why it’s critical to human life. In the following interview, NAD+ expert Dr. Charles Brenner explains in simple terms why we need NAD+ and why we might consider boosting NAD+ levels by supplementing with vitamins such as Nicotinamide Riboside “NR” (FAQs) (Life Changing Consumer Anecdotes):
During a recent panel discussion in Korea, NAD+ expert Dr. Charles Brenner was asked for his reaction to consumers reporting remarkable skin benefits after taking vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Consumer Anecdotes). Here’s his response (video and transcript below):
We’ve heard some inspiring stories from consumers taking matters into their own hands and feeding their cats and dogs NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (Pet Anecdotes). Now comes Jackie with an equally remarkable story about the impact she believes NAD+ supplement NMN had on her ailing cat (please consider sharing your own NAD+ supplement experience using the form below):
In an appearance on the popular “Sheekey Science Show“, NAD+ expert Dr. Charles Brenner was asked about taking NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Consumer Anecdotes) to improve fertility. Here’s what he said (video and transcript below):
In a recently published September 2022 investor presentation (Disclosures: none), there’s a slide highlighting results from some 2020-22 clinical trials studying B3 vitamin Nicotinamide Riboside “NR” (FAQs) (Life-Changing Consumer Anecdotes). Take a look:
In a lengthy Twitter thread yesterday focused on longevity, NAD+ expert Dr. Charles Brenner made a passing comment about vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life-Changing Consumer Anecdotes) that should be of interest to anyone looking to heal from minor cuts or scrapes. Here’s what he said:
A Twitter user recently asked NAD+ expert Dr. Charles Brenner if he’s seen any evidence that boosting NAD+ levels with vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life-Changing Consumer Anecdotes) can lead to increased testosterone levels. Here’s Dr. Brenner’s response:
In a presentation given yesterday entitled “Boosting Resiliency with Nicotinamide Riboside”, NAD+ expert Dr. Charles Brenner talked about vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a potential treatment for those suffering from ALS. The following are his key concluding quotes (full video below):
When purchasing NAD+ boosting supplement Nicotinamide Riboside “NR” (FAQs) (Reviews), you have many decisions to make. Do you buy the 100mg capsules? 300mg? How much should you take daily? And when should you take it? During yesterday’s quarterly earnings call, the Niagen team shared what their internal team does:
Rather than deciding between NAD+ boosting supplements NMN (FAQs and Anecdotes) and NR (FAQs) (Anecdotes), some consumers take NAD+. NAD+ expert Dr. Charles Brenner explains why that doesn’t make sense to him (video and transcript below):
In late 2019, NAD+ expert Dr. Charles Brenner received a research grant from the Gates Foundation to study the various NAD+ precursors including NMN (FAQs and Anecdotes) and NR (FAQs) (Anecdotes). This past week, Dr. Brenner finally provided a peek at what he found (videos and transcripts below):
Earlier today, a caller asked Dr. Drew for his thoughts on NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) (Podcasts). Here’s what he said in response about NR and NMN (FAQs and Anecdotes) (video and transcript below):