A few years ago, a surprising study showed that a large majority of the top 22 NMN brands sold on Amazon contained much less NMN than advertised (Link). Fast forward to mid-2024, a new study has found similar results (and only one NMN brand from the two studies overlapped). Here’s more from the 2024 NMN study:

Excerpts from the 2024 NMN Study:

“Here, Nicotinamide Mononucleotide (NMN) and Urolithin A supplements, easily accessible online or in pharmacies, were tested for their active ingredient content.

Results showed a significant deviation from the labeled amounts, ranging from + 28.6% to -100%. This indicates a considerable disparity in the quality of geroprotective supplements.

…Most of the supplements contained lower amounts compared to label quantities; two of 15 non-liposomal NMN and two of four UA products had higher amounts.

A previous report from ChromaDex (NR/Niagen) found similar results, where 22 brands were tested, and 14 samples were below 1% of NMN claimed amount and three samples had no NMN detected.

There was no overlap in the brands tested in this report and Chromadex (NR/Niagen) report, except for one product (NMN#15), which yielded similar results [27].

…The strength of the study is that very stringent methods for testing NMN and UA were used.

Methods were developed and validated for each experiment, including testing the recovery, precision, accuracy, and matrix effect.

…Each dose of the supplement, capsule, tablet, softgel or sachet was weighed and the actual NMN was calculated”

Comment: You can read the full 2024 NMN study HERE.

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