Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Month: June 2021

On the Joe Rogan Podcast, David Sinclair Agrees NAD Boosters Help Fight Jet Lag

We’ve heard repeatedly that NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) helps people overcome jet lag. What about NAD booster NMN (FAQs and Anecdotes)? Well, on the Joe Rogan podcast earlier this month, Harvard’s David Sinclair said the following:

Why Does Dr. David Sinclair Take NMN Over NR?

Here’s what Harvard professor and aging researcher Dr. David Sinclair said about NMN (FAQs and Anecdotes) vs NR (FAQs) (Anecdotes) on a 2020 podcast (video embedded below):

Anecdote #21: Despite Multiple Threats, This 69-Year Old Attributes His Liver Health to Nicotinamide Riboside (NR)

On multiple occasions, we’ve heard that Nicotinamide Riboside “NR” (FAQs) (Reviews) can provide protection for the liver in conditions of metabolic stress. Our latest consumer reviewer clearly agrees. Here’s his story (please consider sharing your own NAD+ supplement experience using the form below):

A New, Cheaper, Lower Dose Nicotinamide Riboside (NR) Has Arrived. Should You Give it a Try?

Last week, Walmart introduced a new 100mg dose of Nicotinamide Riboside “NR” (FAQs) (Reviews) in partnership with Chromadex. While the FDA recommended daily dose of NR is 300mg, we’ve been told that a dose as low as 100mg can also have a therapeutic benefit. It’s reasonable to assume that since NR is expensive, this new cheaper SKU at Walmart is an effort to target a new consumer group. It also might encourage others who could afford the 300mg dose but either balk at the price or are awaiting more clinical data to finally give it a try. Here’s how Chromadex CEO Rob Fried explained the strategy in a recent interview with the TD Ameritrade Network (video embedded below):

While We Await Clinical Trial Results, Here’s Why Nicotinamide Riboside (NR) Might Help Alzheimer’s Patients

One of the main challenges for vitamin supplement companies is they can’t make health claims. It doesn’t matter how much science might back those claims — the FDA simply won’t allow supplement companies to market to specific disease states. So, how can consumers determine for themselves whether elevating NAD levels with Nicotinamide Riboside “NR” (FAQs) (Reviews) might help reduce the risk for diseases like Alzheimer’s? Well, we know that world renowned Alzheimer’s expert Dr Rudy Tanzi is launching a clinical trial with NR and believes it might work. And then there’s the following from Chromadex CEO Rob Fried on last week’s Patients Rising Podcast:

Certain Diseases that Cause Accelerated Aging are Marked by Low NAD Levels

It’s widely believed that NAD depletion is a fundamental feature of aging. This is particularly evident in certain diseases that cause accelerated aging. Chromadex CEO Rob Fried discussed this in detail on last week’s Patients Rising Podcast:

What are Pre-Clinical Studies Saying about Nicotinamide Riboside (NR) and its Impact on Cancer?

In a recent pre-clinical study, scientists at the Ho Lab looked at NAD booster Nicotinamide Riboside “NR” (FAQs) (Reviews) and its impact on cancer growth. One key conclusion: “Collectively, these findings reveal that supplementation with NR alleviates mitochondrial dysfunction and further induces additive anti-tumor immunity in conjunction with ICB (immune checkpoint blockade) treatments”. These findings are somewhat consistent with what Dr. Charles Brenner (NAD expert and discoverer of NR as an NAD precursor vitamin) has said about NR and cancer on various platforms over the last year:

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