Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Tag: Niagen

If NMN is Safe, Why Don’t Regulators Approve It?

Much to my surprise, lots of people take NAD+ boosting supplement NMN (FAQs and Anecdotes). But as readers of this site know, I’m certainly not one of them. While I’m sold on the importance of boosting NAD+ levels, I defer to the regulatory authorities in charge of evaluating consumer safety to determine which NAD booster to take. And hands down, it’s Nicotinamide Riboside “NR” (FAQs) (Anecdotes). It’s not even close. NR has been deemed safe by the FDA (NDI), Health Canada, EFSA, Australian TGA, and achieved GRAS status — NMN has received none of these approvals. What about the general science community? Well, they’ve clearly made their choice, too. There are currently 67 human clinical trials at some stage testing NR as a treatment for various diseases — only 14 trials for NMN. This suggests that scientists overwhelming choose NR when testing NAD boosters on human subjects. As well, the scientists at Nestlé chose NR over NMN when launching new food and beverage products selling to the general population. But while NR appears the safe choice, it remains abundantly concerning that even with the lack of regulatory body safety recognition, there’s obviously so much consumer demand for NMN that there are MANY companies still selling it. And each of these companies is selling something different. So it’s virtually impossible to know what you’re actually ingesting when taking NMN. And yet NMN remains incredibly popular. It’s a marketing triumph of significant proportions that so many consumers have been convinced to put something in their bodies that has so many red flags in plain sight. And then comes this:

Is There Added Benefit to Taking Nicotinamide Riboside (NR) Sublingually?

On numerous occasions, Dr. Charles Brenner (who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin) has responded to questions about taking NR under the tongue:

If Niacin Boosts NAD, Why Pay Up for Nicotinamide Riboside (NR)?

Here’s what Dr. Charles Brenner (who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin) said in response to a question about boosting NAD with NR vs Niacin on Twitter yesterday:

Should You Consider NAD IV Drip Therapy?

In a segment on last week’s Darin Olien podcast (“Understanding Human Metabolism”), NAD expert Dr. Charles Brenner made the case against “NAD IV drip therapy” (a treatment often endorsed by Joe Rogan). Dr Brenner’s suggestion: Oral supplementation with Nicotinamide Riboside “NR” (FAQs) (Reviews). Key quotes and podcast embedded:

Harvard Trained Fertility Specialist Recommends Vitamin Supplement Nicotinamide Riboside (NR) to Improve Egg Quality

When IVF didn’t work for Dave Crouse and his wife, they turned to NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). After 3 months of NR supplementation (1000 mg daily), Dave’s wife conceived (“Our Niagen Baby“). Can the Crouse family experience be replicated? Well, Harvard-trained fertility specialist Dr. Aimee Eyvazzadeh AKA “The Egg Whisperer” has said the following on various podcasts including the ones below (videos embedded):

This MD Takes Vitamin Supplement Nicotinamide Riboside (NR) But Feels Nothing. So Why Does He Take It?

Last week, Australia-trained Angus Hays MD joined the Curious Doc podcast to discuss Nicotinamide Riboside “NR” (FAQs) (Anecdotes) and NMN (FAQs and Anecdotes). The host and guest (two medical doctors) do an excellent job of explaining a complicated subject in plain, accessible, and non-scientific English. The following are key quotes (full 15-minute video interview embedded below):

I Missed a Day Taking Nicotinamide Riboside (NR). Is that a Problem?

There are many reasons one might miss a day taking vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). But what does it mean for us? Here’s what the folks at Chromadex said via email in response to a broad question about missing a day of supplementation or simply taking days off:

New Nicotinamide Riboside (NR) Fertility Study Supports Claim Made in Reader Submitted Anecdote “Our Niagen Baby”

Almost a year ago, airline pilot Dave Crouse shared a life-changing anecdote about welcoming a new baby following seemingly insurmountable fertility challenges. He attributed he and his wife’s success to vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Is Dave correct that NR helped lead to his new baby? Well, last week a new study was published suggesting there might be some validity to Dave’s claim. And in a Facebook comment responding to the new results, Dave explained in further detail how this specific study mirrored his own experience in which he believes NR ultimately helped: “Age-related Oocyte quality was the reason IVF did not work for us”. The following once again is Dave and his wife’s story, “Our Niagen Baby” (Anecdote #11):

INTERVIEW: Expert Compares Nicotinamide Riboside (NR), Niacin, and Nicotinamide

Dr. Charles Brenner (FAQs), University of Iowa professor, chief scientific advisor at Chromadex, and discoverer of Nicotinamide Riboside “NR” (FAQs) as an NAD precursor vitamin recently responded to a number of investor questions. Key quotes:

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