At a conference last year, Dr. Charles Brenner (FAQs), who discovered Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as an NAD precursor vitamin discussed the safety of NR. Here’s what he said (video and transcript below):

At the 35:50 mark of the video embedded below:

“So, now there’s a clinical trial track record for NR and I’ll just summarize it here.

First, safety.

So, we’ve done multiple safety trials up to two grams of NR per day for up to 12 weeks.

I think that there are much longer trials that have been completed now.

We’ve never seen any serious adverse events that are attributable to NR.

If you have enough participant days, someone will have a headache or a stomach ache.

But you don’t see an excess of this in the NR participants.

You see basically the same types of events in the placebo”

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