Chromadex reported Q1 2020 earnings results yesterday. The following are key quotes from management’s earnings call relating to NAD+, Nicotinamide Riboside “NR” (FAQs) (Reviews), and COVID-19:

On Repeat Customers

“People who buy TRU NIAGEN tend to continue to buy TRU NIAGEN particularly those who have taken it for more than a couple of months.”

On Research Showing COVID-19 Decimating NAD; Cells Demand NR

“Recently, we announced the first round of results of a combination tissue and in vitro study led by Dr. Charles Brenner, our Chief Scientific Officer and one of the world’s foremost experts in NAD research, as well as Dr. Stan Perlman, one of the leading experts on coronavirus.”

“Dr. Brenner’s preclinical study showed 2 key findings.”

“One, a COVID-19 introduction to the studied cells caused greater than three-fold reduction in NAD.”

“And Two, these infected cells specifically sought out nicotinamide riboside (NR), NIAGEN, in an attempt to replenish NAD levels in the face of the viral infection. We expect additional research from Dr. Brenner to be made public soon.”

“The next phase of his preclinical research will explore whether introducing nicotinamide riboside (NR) NIAGEN may support cells innate immune response to coronaviruses and other viruses.”

On Plans to Show NR Rescues NAD Supply in Coronavirus

“…there’s been quite a bit of research over the past few months or so that’s published essentially showing the decline of NAD or NAD under attack in coronavirus.

“It’s the same story we’ve been saying as a product since the beginning — NAD comes under attack with age. It comes under attack in this case in a coronavirus infection.

“…that process of the cell defending itself is utilizing NAD and it’s also knocking down the virus — it’s attacking the supply of NAD by knocking down the supply of NAD.

“So it’s very similar to the aging story, it’s just happening in days rather than in years.”

“So…we have to do studies confirming the link between nicotinamide riboside’s (NR) ability to essentially rescue or raise NAD when it’s getting knocked down in that coronavirus cell.”

“…we don’t have to prove that NR can raise any NAD, we know it does that. Multiple human studies have shown that nicotinamide riboside (NR) is safe and multiple studies have shown that nicotinamide riboside (NR) is in fact very much capable of raising NAD levels.”

“What we need to do here in connecting the dots is just showing that in this particular model that we can successfully use nicotinamide riboside or NIAGEN to rescue NAD supply in coronavirus…..

On Management’s Conservative Messaging for NR’s Impact on COVID-19

“As you’ve noticed, we don’t market beyond the published data and there is some published data on the impact of viruses on NAD and now we have some additional data specifically relating to coronavirus.

“But there’s limited data on the impact of coronavirus — of the impact of NIAGEN on coronavirus especially in a human study. We are working on it and as the data comes out we will communicate that data.

“Anything that’s preclinical can be marketed to healthcare practitioners but cannot be marketed to consumers. And you know we’re very careful in the way we communicate these messages.

“So we are working vigorously to get these studies out. There are several under way.

“But we are not tone deaf about what the market is looking for. The market wants to understand how TRU NIAGEN could impact their risk for viruses in general and coronavirus specifically.

“We did slightly adjust or add to our messaging and show that cell defense and NAD and NIAGEN are related. We are showing a positive benefit to that shift in messaging but until we have some published information, scientific studies we’re not going to be able to make the full message clear.

On the Launch of TRU Niagen Beauty at Watsons in Hong Kong

“TRU NIAGEN Beauty, which launched in stores in late April. TRU NIAGEN Beauty builds on the success of the TRU NIAGEN brand as an award-winning and best-selling health product among Watsons Hong Kong loyalty members as well as driver of their healthcare category. TRU NIAGEN Beauty will allow us to reach new demographics seeking our science-based solutions for their beauty routines.”

On NR as Potential Therapy for Cardiac Arrhythmic Disorders

“In April, a preclinical study demonstrating the effects of both niacinamide and our product nicotinamide riboside (NR) supplementation on Cardiac Electrophysiology was published in the Journal of Molecular and Cellular Cardiology.

“Researchers from the University of Iowa were able to demonstrate that both NR and NAM increased NAD and NADH levels. However, only NR indicated a potential cardiovascular effect.

“These results reinforce earlier preclinical findings that suggest increased NAD levels may have a beneficial impact on cardiac conditions in arrhythmias. The researchers concluded that the results warrant further investigation into NR as a potential therapy for cardiac arrhythmic disorders.

On Human Trials Using NR

“Since our last call, publication of research on NR and NAD has continued to accelerate with the publication of the ninth human trial and multiple preclinical studies.”

“There are 40 ongoing, completed, and published clinical trials currently registered on clinicaltrials.gov to investigate the pharmacokinetics and the therapeutic effects of NR.”

“An additional nine clinical trials are registered to test NR in combination with other ingredients for a total of 49.”

On Consumer Demand for Immune Support Going Forward

“I believe that fundamentally that there’s going to be a demand for immune support related products ongoing well past this — this goes out. I mean it’s — I think people are going to be concerned. They’re going to be worried about their immune support in general. And in reality, I think that’s what the data is going to show us that NAD plays a central role in a healthy immune system. And that’s going to be not only immediate I think it’s going to be a long lasting effect.”

Full Chromadex earnings call transcript HERE.

RELATED:

  • FAQs on taking NAD boosting vitamin supplement Nicotinamide Riboside (NR) can be found HERE.
  • NR supplementation may have helped sufferers of these diseases & conditions (Consumer Reviews)

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