Chromadex CEO Rob Fried joined the “Mottek on Money” radio show yesterday. His concluding message on flagship product Nicotinamide Riboside “NR” (FAQs) (Reviews): “…the growth has been fairly dramatic and we expect it to continue as more people become aware of how taking this thing can impact your health, help you to heal, help you to grow, help you to have more energy, and essentially help you to age.” The following are other key quotes (link to podcast below).

Chromadex CEO on “Mottek on Money” (interview at 22:00 minute mark)

“…Chromadex is a company that sells a dietary supplement called TRU Niagen….the flagship product of the company.

The science behind TRU Niagen is quite unique and quite exciting — and has the potential to benefit many, many people.”

Question: What does it do for you? It’s an anti-aging product?

“We position it as anti-aging product because what TRU Niagen does is — the active ingredient in TRU Niagen is called Nicotinamide Riboside (NR).

Nicotinamide Riboside (NR) is a very novel form of Vitamin B3 — in that it elevates a coenzyme inside all living cells called Nicotinamide Adenine Dinucleotide (N.A.D.) otherwise known as NAD.

NAD is a coenzyme that’s involved in every important metabolic function within the cell but most notably energy metabolism, bioenergetics — the ability to convert nutrients from food and oxygen from air into energy within the cell.

And that’s done by an organelle inside the cell called mitochondria.

So, mitochondria, in order to create energy require NAD.

But NAD declines with age.

So if you take Nicotinamide Riboside (NR) — we’ve had many published studies clinical and pre-clinical that have proven that we not only elevate NAD but we actually elevate energy production and mitochondrial function.

So, you actually physically have more actual energy inside the cell if you take TRU Niagen.

Now I know if you drink a cup of coffee you may feel like you have more energy.

But, indeed what coffee does is it stimulates the brain — you feel that you have more energy. It doesn’t actually create energy.

But if you take TRU Niagen you actually will have more energy — in fact, we have studies that indicate that we not only have more energy but we actually have more mitochondria.

There’s one study made public that indicates that when you take TRU Niagen it elevates mitochondrial biogenesis in muscle tissue — actually more mitochondria.

But the other thing NAD is important for is the repair of the cell.

And current thinking in the anti-aging industry about how to fight aging is to increase the cell’s ability to repair itself.

Aging itself is the accumulation of damage at the molecular and cellular level.

But, when we’re young, cells have a remarkable ability to repair damage as it happens.

And this repairing of damage within a cell is reliant on an enzyme series called PARP enzymes.

PARP enzymes are intensely NAD dependent.

But what PARP enzymes do is they repair damage is it happens.

And what we’ve also shown is when you take TRU Niagen we upregulate PARP enzymes — actually increase the effectiveness and number of PARP enzymes.

So, by taking this you not only increase energy metabolism but you increase the cell’s ability to defend itself or repair itself.

So, this is why we refer to it as an anti-aging dietary supplement — but when you get down into the details of what it actually does is it increases NAD.”

Question: Does this have application here as far as therapeutic use for treatment of COVID-19?

“It very well might.

There was a study that was unpublished that was done several years ago by Dr. Stan Perlman at the University of Iowa who’s recognized as one of the nation’s leading researchers on COVID and coronavirus.

And what he showed was when a coronavirus attaches to a cell NAD levels in that cell decline rapidly.

So, back in March we replicated that study and indeed we were able to show that when a coronavirus attaches to a cell NAD levels decline and PARP levels go up, upregulate.

Why?

Because the cell is trying to ward it off and defend itself.

We made that study public on bioRxiv in April.

Then we did a follow-up study that we published on bioRxiv in July that showed when you add Nicotinamide Riboside (NR) to the solution it’s protective against the Coronavirus.

So that data was interesting and we then announced shortly thereafter a collaborative research agreement with with the NIAID — that’s the infectious disease lab in Colorado part of the NIH which is overseen by Dr Anthony Fauci — where they are presently doing a study on animals — they replicated the coronavirus disease in hamsters and mice and they’re measuring the impact of Niagen on those animals.

In the meantime, a study was published on MedRxiv last week which was conducted in Turkey on 100 hospitalized COVID patients.

These were patients who had mild to severe symptoms.

And of the 100, 77 of them received the standard of care local in Turkey plus a cocktail of dietary supplements that featured TRU Niagen, Nicotinamide Riboside (NR).

The other 22 patients received the local standard of care and a placebo — meaning a drink that had nothing in it.

And it turned out that the 77 patients who received the dietary supplement cocktail recovered 30% quicker.

They were asymptomatic 30% faster than the group that did not receive the dietary supplement cocktail.

So, that’s a human clinical study and is consistent with the other two studies that I announced before.

And mechanistically we understand — because coronavirus is a virus like any virus and it attacks the cell and penetrates the cell.

And we know that when you elevate NAD levels by taking TRU Niagen you’re strengthening the cell.

So, it’s intuitive that there might be a benefit.

So, that’s why these studies are taking place and we’re trying to contribute a solution to the problem.”

On TRU Niagen Consumer Adoption

“…the growth has been fairly dramatic and we expect it to continue as more people become aware of how taking this thing can impact your health, help you to heal, help you to grow, help you to have more energy, and essentially help you to age.”

RELATED:

  • LISTEN to the show HERE.
  • FAQs on taking NAD boosting vitamin supplement Nicotinamide Riboside (NR) can be found HERE.
  • NR supplementation may have helped sufferers of these diseases & conditions (Consumer Reviews)

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