It’s widely believed that NAD depletion is a fundamental feature of aging. This is particularly evident in certain diseases that cause accelerated aging. Chromadex CEO Rob Fried discussed this in detail on last week’s Patients Rising Podcast:

At the 18:30 mark of the podcast below:

“There are a number of orphan diseases that cause accelerated aging.

There’s one in particular called Cockayne Syndrome in which children age so rapidly that they generally die of old age by the time they’re age 12 or 13.

So, these children who have Cockayne Syndrome — but also some of these other — Citrin disease is another one we recently announced we’re doing a study on — Hypoxia, Werner’s disease — these are all diseases that are age related.

These diseases are also generally associated with extremely low in some cases non detect levels of NAD.

So, the NIH did a mouse study on Cockayne’s Syndrome and they showed that they were able to treat these mice who were clearly NAD deficient and had a Cockayne’s equivalent with Nictotinamide Riboside (NR), with Niagen.

The idea here is that by elevating NAD these kids who were aging very rapidly can do better.

But in many respects we all have a version of this disease.

We’re all aging a little bit every day.

But with these diseases what you see is a human cohort group a sample group of people who are aging so rapidly that you can potentially see a benefit here.”

RELATED:

  • More on NAD and aging HERE.
  • NR supplementation may have helped sufferers of these diseases & conditions (Consumer Reviews)
  • FAQs on taking NAD boosting vitamin supplement Nicotinamide Riboside (NR) can be found HERE.

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