In a wide-ranging and ongoing AMA on the NR subreddit, Harvard trained fertility specialist Dr. Aimee (“the egg whisperer”) was asked whether one can continue to take NAD+ boosting supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes) while pregnant. Here’s what she said:

Question:

“Hi, Dr Aimee, can i take TruNiagen while pregnant?

Dr. Aimee (“the egg whisperer”):

“I would talk to your doc about what they recommend in pregnancy.

I can definitely share what I tell my patients: I tell them continue it until approximately 7 weeks of pregnancy.

This recommendation is based on 2 animal study and 1 human study showing it may help prevent birth defects.

Some patients choose to take it the entire pregnancy and I support them with this decision.

It may also reduce risk of pre eclampsia

https://pmc.ncbi.nlm.nih.gov/articles/PMC7035598/ (“NAD deficiency due to environmental factors or gene–environment interactions causes congenital malformations and miscarriage in mice”)

https://pmc.ncbi.nlm.nih.gov/articles/PMC9541200 (“NAD+ deficiency in human congenital malformations and miscarriage: A new model of pleiotropy”)

https://www.life-science-alliance.org/content/7/12/e202302505 (“NAD+ depletion is central to placental dysfunction in an inflammatory subclass of preeclampsia”)

Related:

  • Consumers, Fertility Specialists (DR. Aimee), and NAD+ Experts discuss taking oral supplement NR to boost fertility chances, egg quality (Link)
  • NAD+ boosting supplement Nicotinamide Riboside “NR” (Consumer Reviews)

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