During a recent podcast, Dr. Charles Brenner (FAQs) was asked how NAD+ booster Nicotinamide Riboside “NR” (FAQs) (Anecdotes) impacts inflammation. Here’s what he said:

From “Getting Real About Living Forever — Dr. Charles Brenner” (at 14:20 mark)

HOST:

“When I think of how we can repair ourselves, I think of the inflammatory cascade.

And inflammation can be — it’s our life source.

And it can also be our greatest detriment.

How does NR play in the anti-inflammatory…?

DR. Charles Brenner:

“So, the first human result that had a really clearly positive result, a first human trial…

There were older men in the UK.

I was on a paper.

It was Elhassan and co-workers.

And, in a placebo-controlled trial, NR lowered inflammatory markers — things like IL6, IL10.

And, that’s great because this chronic inflammation is associated with a lot of bad outcomes.

As you said, inflammation is what the body is trying to do to defend itself.

So, it’s not in itself a bad thing.

But, the chronic inflammation is something that can essentially age you.

And we think that due to this anti-inflammatory mechanism, that that is the basis for protection against things like COVID infection.

So, we showed that Coronavirus induces a process that attacks NAD, turns on five genes that use up NAD in trying to fight the infection, and then that led to a phase 2, 3 trial in Sweden and Turkey, I think.

And that showed that NR in combination with three other over-the-counter molecules accelerated time to recovery from COVID.

And we think that NR was the critical active ingredient.

And that’s not just me thinking that.

There’s about four follow-up studies where it’s NR alone.

Should try to protect the kidney in COVID, probably trying to protect it and support recovery in Long COVID, which is also an inflammatory condition”

Related:

  • 4 Consumers Explain Experiencing Reduced Inflammation After Taking B3 Vitamin Nicotinamide Riboside “NR” (Link)
  • NR for Long COVID (Link)
  • Nicotinamide Riboside “NR” (FAQs) (Reviews)
  • Twitter: @RaisingNAD