Scientific studies & consumer anecdotes about healthier living by reversing NAD+ decline (for information purposes only)

Category: Alzheimers

What Is Really Known About the Effects of Nicotinamide Riboside Supplementation in Humans?

On July 21st, Science published a paper entitled “What is really known about the effects of nicotinamide riboside supplementation in humans“. Below is the authors’ conclusion followed by reaction from Dr. Charles Brenner (FAQs) who discovered Nicotinamide Riboside “NR” (FAQs) (Anecdotes) as an NAD+ precursor vitamin:

On a New Podcast, Dr. Vilhelm Bohr Discussed His Alzheimer’s Research, and the Benefits of Nicotinamide Riboside (NR)

On a podcast published this week entitled “An NAD Booster That Improves Cellular Health In The Brain“, Dr. Vilhelm Bohr, a molecular biologist, professor at the University of Copenhagen, and former chief of the Laboratory of Molecular Genetics at the National Institute on Aging (NIA), discussed his Alzheimer’s research, and his enthusiasm for NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Dr. Bohr’s research reminds us of similar work by Alzheimer’s expert Dr. Rudy Tanzi. The following is an excerpt from Dr. Bohr’s podcast interview (transcript and video below):

Here’s the Missing Clip on Supplements from Alzheimer’s Expert Dr. Rudy Tanzi’s Recent Appearance on the “In The Bubble” Podcast

If you listened to former White House advisor Andy Slavitt’s recent podcast “Are We on the Verge of Curing Alzheimer’s?“, you learned a lot. But you were also surprised by the way it ended. Slavitt was joined by world renowned Alzheimer’s experts, Dr. Paul Aisen and Dr. Rudy Tanzi. Toward the end of the podcast, Dr. Aisen advised those interested in taking measures to prevent Alzheimer’s that taking supplements made no sense. You’d have expected a response from Dr. Tanzi, since we know he disagrees. But none came. So, we, at RaisingNAD reached out to Dr. Tanzi, and learned that his response to Dr. Aisen was edited out. Fortunately, the folks at Lemonada were kind enough to share Tanzi’s comments with us, which we’ve embedded and transcribed below:

Should Consumers Start Taking NR, Especially if They Have Risk Factors for Alzheimer’s? A Scientist Weighs In

You’re likely aware of the recently published and very encouraging clinical results using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes) in a study relating to Alzheimer’s. If you missed it, you can catch up here and here. Late last week, the lead investigator, Dr. Christopher R. Martens gave a podcast interview to discuss results of his study. Here’s a key excerpt (podcast embedded below):

In an Interview, Scientist Discusses Key Findings from His Alzheimer’s Related Study Using NR

In late December, Dr. Christopher R. Martens and his team at the University of Delaware published results of a study using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes). The title of their paper is “Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin“. You can read it HERE. Earlier this week, Dr. Martens was interviewed by MedicalResearch.com wherein he discussed his findings. Here are some excerpts:

Video: First Human Trial Shows NR Can Enter The Brain And Reduces Biomarker For Alzheimer’s

Late last year, results of a human clinical study were published supporting the idea that NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Life Changing Anecdotes), upon reaching the brain, can alter the metabolism of certain biological pathways involved in neurodegenerative diseases like Alzheimer’s. For the non-scientist, the following articles (one and two) explain the findings in plain English. For those interested in the science, see the following short video (6 minutes):

Parkinson’s Expert: Here’s My Advice for Consumers Looking to Prevent Neurological Disorders Such as Parkinson’s

During the Q&A portion of last week’s presentation, Parkinson’s expert Dr. Charalampos (Haris) Tzoulis was asked if, based on his ongoing clinical trials studying vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Anecdotes), he had any advice for consumers looking to prevent neurological disorders such as Parkinson’s. Here’s what he said:

What Does One of the Top Alzheimer’s Researchers Think about the Latest Alzheimer’s Study Including Nicotinamide Riboside “NR”?

Last week, results of a clinical study were released bringing new hope for Alzheimer’s patients: “Our results indicate that treatment of AD patients with CMA (full list) can lead to enhanced cognitive functions and improved clinical parameters associated with phenomics, metabolomics, proteomics and imaging analysis.” While this is clearly encouraging news, we’re quick to defer to the expertise of those better positioned to analyze the study results to tell us what they mean. And there’s no one better than Alzheimer’s expert Dr. Rudy Tanzi — who also happens to be a passionate consumer of one of the CMAs in the latest study, Nicotinamide Riboside “NR” (FAQs) (Reviews).

Can Nicotinamide Riboside “NR” Help Those with ALS?

In a presentation given yesterday entitled “Boosting Resiliency with Nicotinamide Riboside”, NAD+ expert Dr. Charles Brenner talked about vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a potential treatment for those suffering from ALS. The following are his key concluding quotes (full video below):

New Phase 1 Clinical Trial Results Show B3 Vitamin Nicotinamide Riboside (NR) as a Potential Neuroprotective Therapy for Parkinson`s Disease. Why is This Important?

We know there’s significant interest in NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) as a potential treatment for Alzheimer’s Disease (Link). It appears the same can now be said for NR and Parkinson’s. The following are results of a Phase 1 clinical trial published yesterday (Note: A Phase 2 study is already underway):

WebMD: The End of Alzheimer’s; How New Treatments (e.g. Nicotinamide Riboside “NR”) Might Rewrite The Long Goodbye

In a lengthy WebMD piece published earlier today, Lisa Marshall details her father’s depressing decline at the hands of Alzheimer’s disease. Despite her father’s death, Marshall explains there’s reason for hope. Scientists are exploring possible ways of fighting back against Alzheimer’s including the use of NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). Key excerpts from the WebMD piece:

FAQs on the Potential for Nicotinamide Riboside (NR) in Alzheimer’s Patients

Harvard’s Dr. Rudy Tanzi is a leading expert studying Alzheimer’s disease. He also happens to be a passionate believer in NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). As a result of his lab work, he’s launching a clinical trial looking at NR in individuals with mild cognitive impairment (MCI) and mild Alzheimer’s dementia (AD) (actual start date March 2, 2022). Here’s why:

What’s the Latest on the Parkinson’s Study Using B3 Vitamin Supplement Nicotinamide Riboside (NR)?

We know that world renowned Alzheimer’s expert Dr. Rudy Tanzi believes in B3 vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). He takes NR daily, he’s conducting a clinical trial studying NR as a possible treatment for Alzheimer’s, and he also recently recommended it to Dr. Oz’s mother who’s currently suffering from that very debilitating disease. What about NR as a possible treatment for Parkinson’s? There’s reason to believe NR could help. Here’s the latest on a recent Parkinson’s/NR clinical trial out of Norway:

Dr. Oz’s Mom Has Alzheimer’s; Her Regimen Includes B3 Vitamin Nicotinamide Riboside (NR)

In a segment this week entitled “What Regimen Does Dr. Oz Have His Mother On In Her Battle Against Alzheimer’s?”, Dr. Oz talked to Dr. Rudy Tanzi, Alzheimer’s expert and Professor of Neurology at Harvard. Dr. Tanzi offered a series of recommendations including taking NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews).

What’s Chromadex’s Reaction to the Recent Nicotinamide Riboside (NR) Cocktail Study on Alzheimer’s?

From last night’s Chromadex (Nicotinamide Riboside “NR” (FAQs) (Reviews)) earnings call:

While We Await Clinical Trial Results, Here’s Why Nicotinamide Riboside (NR) Might Help Alzheimer’s Patients

One of the main challenges for vitamin supplement companies is they can’t make health claims. It doesn’t matter how much science might back those claims — the FDA simply won’t allow supplement companies to market to specific disease states. So, how can consumers determine for themselves whether elevating NAD levels with Nicotinamide Riboside “NR” (FAQs) (Reviews) might help reduce the risk for diseases like Alzheimer’s? Well, we know that world renowned Alzheimer’s expert Dr Rudy Tanzi is launching a clinical trial with NR and believes it might work. And then there’s the following from Chromadex CEO Rob Fried on last week’s Patients Rising Podcast:

Top Alzheimer’s Expert Formally Announces Much Anticipated Long-Haul COVID Study Using Supplement Nicotinamide Riboside (NR). Why is This Important?

In numerous recent interviews (Here and Here), top Harvard Alzheimer’s expert Dr Rudy Tanzi discussed plans to initiate 2 human clinical studies using NAD+ boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews). In one study, Dr Tanzi will focus on Alzheimer’s patients. And in the other, which was posted on ClinicalTrials.gov earlier this week Dr Tanzi will focus on long-haul COVID patients experiencing persistent cognitive and physical symptoms. You may remember that Dr Tanzi knows a lot about NR through both personal supplementation (“I religiously take Tru Niagen“) AND his association with the NFL’s New England Patriots. As a result, many have been eagerly awaiting these two clinical trials. Here’s more on the COVID trial posted earlier this week:

A Look at the All-Star Team of Scientists Studying the Potential of Nicotinamide Riboside (NR)

We know that there’s enormous interest in studying Nicotinamide Riboside “NR” (FAQs) (Reviews) in the science community. A quick look at the 50+ ongoing or completed clinical trials says it all. But who are these scientists? Chromadex CEO Rob Fried talked about some of them at the Oppenheimer Health Care Conference yesterday.

Popular YouTube Health Channel Puts Nicotinamide Riboside (NR) at the Top of List of Brain Supplements

A popular YouTube channel called Bestie (3.4m subs) posted a short but substantive video this week with Nicotinamide Riboside “NR” (FAQs) (Reviews) topping a list of “6 Supplements That’ll Help You Build A Better Brain” (Turmeric, Lion’s Mane Mushrooms, Seafood, Vitamin D3). Transcript and video embedded below.

10 Most Popular Posts

As the share price of Chromadex increased dramatically this week, many investors learned about Nicotinamide Riboside “NR” (FAQs) (Reviews) for the first time. The following are RaisingNAD’s most popular blog posts of the last year:

Should Those Suffering from Parkinson’s Disease Supplement with Nicotinamide Riboside (NR)?

We know that one of the world’s top Alzheimer’s experts recently initiated clinical trials testing vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) on human patients. But what about Parkinson’s disease? Both Dr David Sinclair and Dr Charles Brenner agree that there’s good reason for clinical trials testing NAD boosters on those suffering from neurodegenerative diseases. So, what’s the latest? Dr. Brenner (NAD expert and discoverer of NR as an NAD precursor vitamin) made the following comment on Twitter earlier this week.

Harvard Alzheimer’s Expert Explains Why “I Religiously Take Tru Niagen” (Nicotinamide Riboside “NR”)

In a mid-November podcast appearance, Harvard neuroscientist and Alzheimer’s expert Dr. Rudy Tanzi made a compelling case for supplementing with Nicotinamide Riboside “NR” (FAQs) (Reviews). This week, he joined host Linda Cooper on “The New 100 Longevity Campaign” and shared even more. The following are key quotes.

Why Do I Take NAD Booster / Health Supplement Nicotinamide Riboside (NR)?

Since launching this site in mid-2020, the goal has been to learn as much as possible about NAD boosting vitamin supplement Nicotinamide Riboside “NR” (FAQs) (Reviews) in order to determine whether to take it myself. I had MANY questions. What’s NAD? How does elevating NAD levels improve my health? Is NR the best way to elevate NAD. levels? Who else takes NR? And the list goes on. So, I started this quest for answers with a very basic question:

VIDEO: Star Neuroscientist Takes Nicotinamide Riboside (NR); Starting Clinical Trials for Alzheimer’s & COVID

Dr Rudy Tanzi is a Harvard neuroscientist, Director of the Genetics and Aging Research Unit at Massachusetts General Hospital, pioneer in identifying genetic markers for Huntington’s and Alzheimer’s diseases, Chair of the Cure Alzheimer’s Fund Research Leadership Group, and author of several best selling books. This week he joined The Genius Life Podcast with Max Lugavere (video embedded below). The following are key quotes on upcoming human trials, why he supplements with Nicotinamide Riboside “NR” (FAQs) (Reviews), and why he increased his dose during the COVID-19 pandemic.

On the Joe Rogan Podcast, Dr. Rhonda Patrick Says “Before I Would Do Something Like That (NAD IV), I’d Probably Try the Nicotinamide Riboside (NR)”

Educating the public about NAD is a monumental challenge. And it’s obviously key to those companies selling NAD boosters. But thanks to Dr. Rhonda Patrick of FoundMyFitness the concept of NAD is much more accessible. Here she is on the Joe Rogan Podcast:

PODCAST: More Evidence Nicotinamide Riboside (NR) May Play a Role in Fighting COVID-19

Dr. Charles Brenner (FAQs), who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD boosting vitamin and is actively studying NR’s impact on the treatment of COVID-19 recently joined YOU The Owner’s Manual Podcast (Host Dr. Michael Roizen is Chief Wellness Officer at Cleveland Clinic) to discuss his latest research. Key quotes and podcast embedded below:

PODCAST: New Study Focused on Nicotinamide Riboside (NR) Preventing COVID-19

Dr. Charles Brenner, who discovered Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD boosting vitamin and is actively studying NR’s impact on the treatment of COVID-19 recently joined PRECISIONE: The Healthcast podcast to discuss his latest research. Key quotes and podcast embedded below:

VIDEO: Nicotinamide Riboside (NR) “Greatest Ingredient of All Time”

Chromadex CEO Rob Fried appeared on the Habits and Hustle Podcast to discuss his movie career, NAD+, and Nicotinamide Riboside “NR” (FAQs) (Reviews). Key quotes, podcast link, and video embedded below:

PODCAST: The New Darling Supplement Of The Anti-Aging Industry is Nicotinamide Riboside (NR)

Dr. Charles Brenner (FAQs), University of Iowa professor, chief scientific advisor at Chromadex, and discoverer of Nicotinamide Riboside “NR” (FAQs) (Reviews) as an NAD precursor vitamin joined the Ben Greenfield Fitness Podcast to discuss NAD+, NR, and lots more. Key quotes and podcast embedded:

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